正念训练对广泛性焦虑症病人干预效果的系统评价

Intervention effect of mindfulness training on patients with generalized anxiety disorder:a systematic review

目的:评价正念训练改善广泛性焦虑症病人焦虑及生活质量的效果。方法:计算机检索the Cochrane Library、PubMed、Web of Science、Ovid-EMbase、EBSCO-CINAHL Complete、Scopus、中国生物医学文献数据库、中国知网、万方数据库和维普数据库中有关正念训练对广泛性焦虑症病人干预效果的随机对照试验,检索时限均从建库至2019年12月31日。由2名研究者独立对文献进行筛选、提取及评价后,采用RevMan 5.3软件进行Meta分析。结果:共纳入10篇文献,涉及787例病人。Meta分析结果显示:正念训练可改善广泛性焦虑症病人焦虑[SMD=-1.30,95%CI(-1.70,-0.90),P<0.00001],提高病人生活质量[SMD=2.00,95%CI(0.06,3.95),P=0.04]。结论:现有证据表明,正念训练可有效改善广泛性焦虑症病人的焦虑和生活质量。

Objective:To evaluate the effect of mindfulness training on improving anxiety and quality of life in patients with generalized anxiety disorder.Methods:Randomized controlled trials on intervention effect of mindfulnes s training on patients with generalized anxiety disorder were searched from the Cochrane Library,PubMed,Web of Science,Ovid-EMbase,EBSCO-CINAHL Complete,Scopus,CBM,CNKI,WanFang database and VIP.The retrieval time was from inception to December 31,2019.Meta-analysis was performed by RevMan 5.3 software after two researchers independently screened,extracted and evaluated the literature.Results:A total of 10 RCTs were included,involving 787 patients.Meta-analysis results showed that mindfulness training can improve anxiety of patients with generalized anxiety[SMD=-1.30,95%CI(-1.70,-0.90),P<0.00001];improve the quality of life of patients[SMD=2.00,95%CI(0.06,3.95),P=0.04].Conclusion:Current evidences shows that mindfulness training can effectively improve the anxiety and quality of life of patients with generalized anxiety disorder.