环境中微塑料对母胎健康的影响

Impact of environmental microplastics on maternal and fetal health

微塑料是指粒径小于5 mm的塑料纤维、颗粒或者薄膜,其污染已经成为全球重大环境问题之一。人体通过摄入、吸入和皮肤接触暴露于微塑料。微塑料可通过细胞毒性与干扰信号转导、影响能量动态平衡和新陈代谢、导致免疫功能紊乱,以及作为微生物和有毒化学物质的载体等机制影响母胎健康。本文旨在综述微塑料的理化性质、人体暴露途径、对母胎的不良效应及其作用机制。

Microplastics refer to plastic fibers,particles,or films with a particle size less than 5 mm,and microplastics pollution has become one of the major global environmental problems.Microplastics can be exposed to the human body through ingestion,inhalation and skin contact,affecting maternal and fetal health through mechanisms such as cytotoxicity and signal transduction,energy homeostasis and metabolic disorders,immune dysfunction,and as carriers of microorganisms or toxic chemicals.The purpose of this paper is to review the physical and chemical properties of microplastics,human exposure pathways,maternal-fetal effects,and its mechanisms.