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浅谈冷冻切片乳腺分泌性癌的诊断线索 被引量:2

To discuss the diagnostic clues of breast secretory carcinoma based on the frozen diagnosis
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摘要 回顾性复习1例乳腺分泌性癌临床资料、组织学特点、免疫表型及分子学检测结果,并复习相关文献,浅谈冷冻切片如何识别分泌性癌的诊断线索。我们报道了1例62岁女性,入院乳腺B超发现左乳腺结节(4a类)。术中冷冻切片诊断:左乳镜下形态呈乳腺腺病伴旺炽性导管上皮增生,分泌性癌待常规免疫组织化学后排除。最终常规病理诊断为乳腺分泌性癌。乳腺分泌性癌是一种少见的预后良好的低度恶性肿瘤,冷冻切片诊断较为困难,仔细寻找其诊断的形态学线索,并有效的临床沟通使得避免术中漏诊,使临床进一步的扩大切除或者确保其切缘阴性显得非常有必要。最终确诊需要结合形态学、免疫组织化学及分子学检测。
作者 张冬梅 郑珍 魏建国 Zhang Dongmei;Zheng Zhen;Wei Jianguo(Department of Pathology,Fu Xing Hospital,Capital Medical University,Beijing 100038,China;Department of Pathology,Shaoxing People's Hospital of Zhejiang Province,Shaoxing 312000,China)
出处 《中华病理学杂志》 CAS CSCD 北大核心 2021年第8期969-972,共4页 Chinese Journal of Pathology
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