母体血清中CK AFP结合β-hCG预测胎盘植入的价值

The Predictive Value of CK AFP andβ-hCG in Maternal Serum for Placental Implantation

目的:基于产妇血清中CK、AFP及β-hCG水平,探讨预测胎盘植入的价值。方法:以承德市中心医院产科为例,选择其2017年到2019年经产后病理诊断为胎盘植入的50名产妇作为实验组。随机选择非胎盘植入产妇52例作为对照组。同时对各组产妇血清CK、AFP及β-hCG水平进行测定,数据采用SPSS23.0统计软件进行分析。结果:实验组产妇中,三类指标的水平明显高于对照组,数据经比较,差异具有统计学意义;且三类指标对胎盘植入均有一定的预测价值,而三者结合预测胎盘植入的预测价值更高,灵敏度和特异度分别为70%、81%。血清CK、AFP和β-hCG预测胎盘植入cut off值分别为:153.14U/mL、193.23U/mL和21909U/L。结论:母体血清中CK、AFP及β-hCG三者结合,可以对孕妇分娩前的胎盘植入进行有效的预测,且预测价值相对较高。

Objective:Based on the levels of CK,AFP andβ-hCG in the maternal serum,the value of predicting placenta accreta was explored.Methods:50 cases of puerpera in the obstetrics department of Chengde Central Hospital from 2017 to 2019 who were pathologically diagnosed as placenta accreta were selected as the experimental group.52 cases of non-placental implant women were randomly selected as the control group.The maternal serum CK,AFP andβ-hCG levels were measured in each group,and the datas were analyzed by spss23.0 statistical software.Results:The levels of the three types of indicators in the experimental group were significantly higher than those in the control group.The datas were compared and the differences were statistically significant;and the three types of indicators had a certain predictive value for placental accreta,and the combination of the three indicators has higher predictive value for placenta accreta,with sensitivity and specificity of 70%and 81%respectively.The cut off values of serum CK,AFP andβ-hCG for placenta accreta is 153.14U/mL,193.23U/mL and 21909U/L.Conclusion:The combination of CK,AFP andβ-hCG in maternal serum can effectively predict the placental accreta of pregnant women before delivery,and the predictive value is relatively high.