美洲大蠊提取物对精神疾病患者肠道菌群影响的研究

Effect of Periplaneta americana Extract on Intestinal Flora in Patients with Mental Illness

目的:探究美洲大蠊提取物对精神疾病患者肠道菌群是否有影响。方法:采集19例精神疾病患者发作期和控制期的粪便样本,对其进行微生物共培养,对菌落数进行统计学分析。结果:3类微生物(需养菌、厌氧菌、真菌)的3种样本(空白组、实验组、阳性组)菌落数两两比较,空白组与实验组、空白组与阳性组(除女性和精神分裂特征的需氧菌组)的菌落数差异均有统计学意义(P<0.05)。结论:美洲大蠊提取物对精神疾病患者的肠道菌群有调节作用。

Objective:To investigate whether the extract of Periplaneta americana has an effect on the intestinal flora of patients with mental illness.Methods:Fecal samples collected from 19 patients with mental illness during the onset and control periods were co-cultured with microorganisms,and the number of colonies was analyzed statistically.Results:The number of colonies in each of the three samples(blank group,experimental group,and positive group)of the three types of microorganisms(aerobic bacteria,anaerobic bacteria,fungi)was compared in pairs.The differences in the number of colonies between the blank group and the experimental group,the blank group and the positive group(aerobic bacteria group except female and schizophrenic characteristics)were statistically significant(P<0.05).Conclusion:The extract of Periplaneta americana can regulate the intestinal flora of patients with mental illness.