摘要
Objective:Systemic lupus erythematosus(SLE)is a multi-system autoimmune disease,in which multiple organs are involved.Lupus with pancreatitis(LP)is a rare disease.It is an effective strategy for clinical work to comprehensively study the patho-genesis,diagnosis and treatment of LP.Methods:A report of 42-year-old female patient with intermittent arthralgia more than 10 years,rash,edema on double lower limbs for 7 years.The patient’s condition was worsened for 10 days,given a diagnosis of SLE nausea,vomiting and abdominal pain after admission.Examinations:blood amylase 612 U/L,urine amylase 3,345 U/L.Ultrasound:pancreas swelled with a change in texture,with ascites(medium).Considered as severe acute pancreatitis,the patient was given treatment with 80 mg methylprednisolone qd,0.2 g cyclophosphamide ivgtt qod,fasting.It was required of gastrointestinal decompression,acid suppression,somatostatin inhibiting pancreatic secretion,anti-inflammatory treatment,intraperitoneal perfusion of antibiotics and other symptomatic treatments.The symptoms were relieved after 18 days.Results:Hormones were selected and combined with immunosuppressants to relieve symptoms with the aid of gastrointestinal decompression,acid suppression,somatostatin and anti-inflammatory therapy.Conclusions:It is critical to summarize the characteristics of LP,diagnose early and give individualized treatment in order to relieve LP.
