重症胰腺炎患者行CRRT治疗的时机选择对疗效的影响研究

Study of CRRT Timing on Curative Effect of Patients With Severe Pancreatitis

目的 分析重症胰腺炎(SAP)患者行连续性肾脏替代(CRRT)治疗的时机选择对疗效的影响。方法 本研究共40例研究对象,均为2018年3月至2020年3月在江门市新会区人民医院开展CRRT治疗的重症胰腺炎患者,按照CRRT治疗时间进行分组,分为早期组(确诊为SAP后立即进行CRRT治疗,n=20)与晚期组(出现急性肾功能衰竭后进行CRRT治疗,n=20)。治疗72h后,对比分析两组体征指标、肝功能、肾功能以及血气分析指标。结果 HR、RR、SCr、、ALT、MAP、PaO_(2)以及PaO_(2)/FIO_(2)上,早期组优于晚期组(P<0.05)。结论 确诊为SAP后开展CRRT治疗的效果理想,可有效恢复患者的病情,控制病情进展。

Objective To analyze effect of timing of continuous renal replacement (CRRT) on curative effect of patients with severe pancreatitis (SAP).Methods The paper chose 40 patients with severe pancreatitis received CRRT treatment in our hospital from March 2018 to March 2020 and divided them into early group (immediate CRRT treatment after SAP diagnosis,n=20) and late group (CRRT treatment after acute renal failure,n=20) according to treatment time.After 72 hours of treatment,physical signs,liver function,renal function and blood gas analysis indexes of two groups were compared and analyzed.Results HR,RR,SCR,alt,map,PaO_(2) and PaO_(2)/FiO_(2) of early group was better than late group (P<0.05).Conclusion CRRT treatment after diagnosis of SAP can achieve ideal effect,restore patient’s condition effectively,control disease progress,which can be further applied in clinical practice.