腰硬联合麻醉用于剖宫产产妇中的有效性和安全性

Efficacy and safety of combined spinal epidural anesthesia in parturients undergoing cesarean section

目的观察腰硬联合麻醉(CSEA)用于剖宫产产妇中的有效性和安全性。方法将114例剖宫产产妇按麻醉方式分为对照组和观察组,各57例。对照组采用硬膜外麻醉(EA),观察组采用CSEA。比较两组的麻醉效果。结果观察组镇痛效果优于对照组(P<0.05)。T1~T4时,观察组的MAP、RR、SpO_(2)、SVV变化幅度小于对照组(P<0.05)。T3时,两组的NE、AngⅡ、醛固酮水平均升高,术后24 h逐渐恢复,且观察组低于对照组(P<0.05)。观察组麻醉不良反应总发生率低于对照组(P<0.05)。结论CSEA应用于剖宫产中可提高镇痛效果,利于稳定循环系统、RAAS系统,安全可靠。

Objective To observe the efficacy and safety of combined spinal epidural anesthesia(CSEA)in parturients undergoing cesarean section.Methods A total of 114 parturients undergoing cesarean section were divided into control group and observation group according to anesthesia method,with 57 cases in each group.The control group was given epidural anesthesia(EA),and the observation group was given CSEA.The anesthetic effects of the two groups were compared.Results The analgesic effect of the observation group was better than that of the control group(P<0.05).At T1-T4,the changes range of MAP,RR,SpO_(2) and SVV in the observation group were smaller than those in the control group(P<0.05).At T3,the levels of NE,AngⅡand aldosterone in both groups increased,and gradually recovered at 24 h after operation,and those in the observation group were lower than the control group(P<0.05).The total incidence of anaesthetic adverse reactions in the observation group was lower than that in the control group(P<0.05).Conclusion CSEA applied in cesarean section can improve the analgesic effect,which is conducive to the stability of circulatory system and RAAS system,and is safe and reliable.