遗传性大肠癌患者一级亲属的大肠癌认知水平及其相关因素分析

Characteristics of cognition about colorectal cancer and influencing factors in first degree relatives of hereditary colorectal cancer patients

目的描述遗传性大肠癌患者一级亲属对大肠癌的认知情况,并探讨其影响因素。方法应用精简的香港中文大学《结直肠癌认知调查问卷》和一般资料调查表,对274例遗传性大肠癌患者的一级亲属进行调查,分析该人群的大肠癌认知特点及水平并采用χ^(2)检验、秩和检验、Logistic回归进行影响因素分析。结果遗传性大肠癌患者一级亲属对大肠癌具有较高认知者占60.2%(165/274),部分认知者占23.7%(65/274),较低认知者占16.0%(44/274),有序多分类Logistic回归分析显示,年龄、性别、文化程度、婚姻状况、家庭人均月收入、医疗保险情况、血亲亲属中患大肠癌人数等因素影响遗传性大肠癌患者一级亲属的大肠癌认知水平(P<0.05),年轻、女性、文化程度高、家庭收入高、单身、公费/城镇医疗保险、有商业保险及血亲亲属中患大肠癌人数>4例者大肠癌认知水平较高。结论遗传性大肠癌患者一级亲属的大肠癌认知水平整体较高,但仍有部分研究对象认知水平很低,其大肠癌认知水平受多因素影响,应采取措施提高部分一级亲属的大肠癌认知水平以更好地防治大肠癌。

Objective To describe the status of cognition about colorectal cancer and the screening and its relevant factors among first degree relatives of hereditary colorectal cancer patients in Guangzhou.Methods Totally 274 subjects were investigated by a self-designed demographic questionnaire and the Chinese version of Cognitive Questionnaire for Colorectal Cancer and were analyzed by chisquare test,rank sum test and logistic regressive.Results 60.2%(165/274)cases had a high level of cognition about colorectal cancer,23.7%(65/274)had middle level of cognition about colorectal cancer and 16.0%(44/274)had a low level of cognition about colorectal cancer.Multivariate logistic regression analysis showed that age,sex,degree of education,marital status,family income,medical insurance and the number of cancer patients in his family were related factors(P<0.05).People who were young,female,highly educated,high family income,single,public/urban health insurance,commercial insurance and with more than 4 relatives suffering from colorectal cancer have higher cognitive level.Conclusions The level of cognition about colorectal cancer among first degree relatives of hereditary colorectal cancer patients was a little high.Medical staff should pay attention to relevant factors of health belief in subjects and develop targeted intervention to improve the level of cognition among these subjects and to promote their screening behavior.