急性缺血性卒中患者认知障碍发生的影响因素研究

Study on the influencing Factors of cognitive Impairment in Patients with acute ischemic Stroke

目的分析急性缺血性卒中(AIS)患者发生认知障碍的影响因素,为预防AIS患者认知障碍的发生提供指导。方法回顾性分析渑池县人民医院2018年2月至2020年2月收治的84例AIS患者临床资料,统计患者的性别、年龄、糖尿病史等信息及认知障碍发生情况,分析认知障碍发生的影响因素。结果84例AIS患者中发生认知障碍31例,发生率为36.90%。单因素分析显示,发生认知障碍的AIS患者的年龄(>65岁)、糖尿病史(有)、高血压史(有)、颈动脉内膜厚度(>1.2 mm)、不良生活方式(有)、颞叶卒中均高于未发生认知障碍的患者,差异有统计学意义(P<0.05)。经Logistic多因素分析结果显示,年龄>65岁、糖尿病史、高血压史、颈动脉内膜厚度>1.2 mm、不良生活方式、颞叶卒中均为AIS患者发生认知障碍的危险因素(OR>1,P<0.05)。结论年龄>65岁、糖尿病史、高血压史、颈动脉内膜厚度>1.2 mm、不良生活方式、颞叶卒中均是AIS患者发生认知障碍的危险因素,临床可据此实施相关干预以减少认知障碍的发生。

Objective To analyze the risk factors of cognitive impairment in patients with acute ischemic stroke(AIS),and to provide guidance for the prevention of AIS.Methods The clinical data of 84 patients with AIS admitted to Mianchi County People's Hospital from February 2018 to February 2020 were retrospectively analyzed.The sex,age,history of diabetes and the incidence of cognitive impairment were analyzed,the influencing factors of cognitive impairment were analyzed.Results The incidence of cognitive impairment was 36.90% in 31 of 84 AIS patients.Single factor analysis showed that,the age(>65 years),history of diabetes,history of hypertension,carotid artery intimal thickness(>1.2 mm),unhealthy lifestyle and temporal lobe stroke of AIS patients with cognitive impairment were all higher than those without cognitive impairment,the difference was statistically significant(P<0.05).The results of Logistic multivariate analysis showed that,age>65,history of diabetes,history of hypertension,carotid artery intimal thickness>1.2 mm,unhealthy lifestyle and temporal lobe stroke were risk factors for AIS patients with cognitive impairment(OR>1,P<0.05).Conclusion Age>65 years,history of diabetes,hypertension,carotid intimal thickness>1.2 mm,unhealthy lifestyle and temporal lobe stroke are risk factors for AIS,clinical intervention can be carried out accordingly to reduce the occurrence of cognitive impairment.