藏医催泻疗法治疗慢性乙型病毒性肝炎活动期回顾性研究

Retrospective Study on Treatment of Chronic Hepatitis B with Purgation Therapy of Traditional Tibetan Medicine

目的客观评价藏医催泻疗法治疗慢性乙型病毒性肝炎活动期患者的临床疗效。方法收集既往住院给予藏医催泻疗法治疗的慢性乙型病毒性肝炎患者50例,详细查阅其病例资料,并进行随访,在进行回顾性总结的同时,重点分析患者肝功复常、乙肝两对半及HBV-DNA改善情况。结果随访发现治疗后患者的肝功与治疗前比较改善明显,具有统计学意义(P<0.05);HBe Ag和HBV-DNA与治疗前比较下降明显,差异具有统计学意义(P<0.05);患者的凝血功能亦有改善(P<0.05),另外随访后的血常规和肾功与治疗前比较无明显改变(P>0.05)。结论藏医催泻疗法治疗慢性乙型病毒性肝炎活动期具有一定的临床疗效,但更加确切的结论仍需高质量大样本的试验加以验证。

Objective To objectively evaluate the treatment of chronic hepatitis B with purigation therapy in traditional Tibetan medicine.Methods A collection of 50 CHB patients who had been hospitalized with Tibetan medicine catarrhal therapy were collected,their case data were reviewed in detail,and follow-up was conducted.While retrospectively summarized,the focus was on the analysis of patients’liver function recovery,hepatitis B two and a half and HBV-DNA.Results The follow-up found that the liver function of the patients after treatment was significantly improved compared with that before treatment,which was statistically significant(P<0.05).HBeAg and HBV-DNA decreased significantly compared with those before treatment,and the difference was statistically significant(P<0.05).The patient’s coagulation function also improved(P<0.05).In addition,blood routine and renal function after follow-up did not change significantly compared with before treatment(P>0.05).Conclusion The purgation therapy of traditional Tibetan medicine has a certain clinical effect on the treatment of active chronic hepatitis B.However,more accurate conclusions still need to be verified by high-quality and large-sample trials.