苏子降气汤加减治疗急性加重期慢阻肺的临床效果分析

Analysis of Clinical Effect of Suzi Jiangqi Decoction in Treating Acute Exacerbation of COPD

目的探讨苏子降气汤加减治疗急性加重期慢阻肺的临床效果。方法选择2019年9月-2020年9月该院患者80例,随机分为两组,每组40例,对照组用常规治疗,观察组加用苏子降气汤加减治疗。对比两组生命体征情况、血气和炎性指标及临床疗效。结果治疗前,两组体温、心率及呼吸差异无统计学意义(t=0.061、0.007、0.014,P>0.05),治疗后,观察组体温、心率及呼吸频率均比对照组低,差异有统计学意义(t=12.863、3.987、4.001,P<0.05);治疗前,两组血气和炎性指标差异无统计学意义(P>0.05),治疗后,观察组酸碱度pH、动脉血氧分压(PaO_(2))比对照组高,动脉二氧化碳分压(PaCO2)、白细胞计数(WBC)和C反应蛋白(CRP)比对照组低,差异有统计学意义(t=14.033、2.227、3.988、2.794、2.978,P<0.05)。观察组治疗总有效率为97.5%,高于对照组的77.5%,差异有统计学意义(χ^(2)=7.314,P=0.007)。结论用苏子降气汤加减治疗急性加重期慢阻肺疾病,能够促进患者生命体征的改善,又能较好地调节身体血气和炎性指标,治疗效果良好,可推广。

Objective To explore the clinical effect of Suzi Jiangqi Decoction in the treatment of acute exacerbation of chronic obstructive pulmonary disease.Methods From September 2019 to September 2020,80 patients in the hospital were selected and randomly divided into two groups,40 cases in each group.The control group received conventional treatment,and the observation group received Suzi Jiangqi Decoction plus or minus treatment.The vital signs,blood gas and inflammatory indexes and clinical efficacy were compared between the two groups.Results Before treatment,there was no statistically significant difference in body temperature,heart rate and respiration between the two groups(t=0.061,0.007,0.014,P>0.05).After treatment,the body temperature,heart rate and respiration frequency of the observation group were lower than those of the control group,and the difference was statistically significant(t=12.863,3.987,4.001,P<0.05);before treatment,there was no significant difference in blood gas and inflammatory indexes between the two groups(P>0.05),after treatment,the observation group’s pH,arterial oxygen partial pressure(PaO2)were higher than those of the control group,arterial carbon dioxide partial pressure(PaCO2),white blood cell count(WBC)and C-reactive protein(CRP)were lower than those of the control group,and the difference was statistically significant(t=14.033,2.227,3.988,2.794,2.978,P<0.05).The total effective rate of treatment in the observation group was 97.5%,which was higher than 77.5%in the control group.The difference was statistically significant(χ^(2)=7.314,P=0.007).Conclusion Suzi Jiangqi Decoction for the treatment of acute exacerbation of chronic obstructive pulmonary disease can improve the patient’s vital signs,and can better regulate the body’s blood gas and inflammatory indicators.The treatment effect is good and can be promoted.