摘要
Movement disorders of paraneoplastic etiology are very rare,representing solely about 1%of all paraneoplastic neurological syndromes.^([1])The most frequently associated carcinoma is small-cell lung cancer,although several others are reported such as hematologic,bowel,breast,prostate and bladder.It was reported an association with CV2/CRMP5,Anti-Hu/ANNA,CASPR2 and Yo antibodies,which are detectable in serum in most cases,isolated or in association.^([1-4])However,in a minority of cases an autoantibody cannot be detected.^([1])The antibody most frequently associated with paraneoplastic chorea is CV2/CRMP5,followed by Anti-Hu/ANNA.