孤立性脑桥梗死患者急性期病情进展的危险因素分析

Analysis of the Risk Factors in the Progression of Patients with Acute Isolated Pontine Infarctions

目的探讨孤立性脑桥梗死患者急性期病情进展的危险因素。方法收集华润辽健集团铁煤总医院2017年1月--2020年12月收治的120例孤立性脑桥梗死急性期患者,对120例患者的临床资料进行回顾性分析。将病情加重的58例作为观察组,将病情无加重的62例作为对照组。比较两组临床资料,采用logistic回归分析孤立性脑桥梗死患者急性期病情进展的危险因素。结果单因素分析显示,女性、吸烟史.糖尿病史.脑卒中史、肌酸激酶水平.梗死部位及血管病变情况,是引起孤立性脑桥梗死患者急性期病情进展的危险因素。多因素logistic回归分析显示,女性、肌酸激酶高.高f血糖.颅内血管病变以及脑桥下段梗死是孤立性脑桥梗死患者急性期病情进展的危险因素。结论孤立性脑桥梗死患者急性期病情进展的危险因素较多,应采取针对性干预措施,以提高患者的预后。

Objective To investigate the risk factors in the progression of acute isolated pontine infarction(IPI).Methods A total of 120 patients with IPI treated in China Resources Liaojian Group Iron Coal General Hospital from January 2017 to December 2020 were collected,and the clinical data of 120 patients were retrospective analyzed.Fifty-eight cases aggravated as the observation group,and the other 62 patients with no aggravation were as the control group.The clinical data between the two groups were compared,and the risk factors in IPI patients were analyzed by logistic regression.Results Univariate analysis showed that,female,smoking history,diabetic history,stroke history,creatine kinase level,infarction site,and vascular disease,are risk factors in the progression of acute IPI.Multivariate logistic regression analysis indicated that female,high creatine kinase,high blood sugar,intracranial vascular lesions,and infarction of the end of brain bridge are risk factors in the acute period of IPI patients.Conclusion There are more risk factors in the progression of patients with IPI,and targeted interventions should be taken to improve the prognosis of patients.