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瞬时受体电位阳离子通道蛋白6在肾脏疾病中的研究进展

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摘要 瞬时受体电位阳离子通道蛋白6(TRPC6)在细胞钙信号通路传导中发挥了非常重要的作用。TRPC6为重要的足细胞膜蛋白并在维系足细胞正常生物学功能中起到重要作用,TRPC6基因突变在临床上能引起蛋白尿的发生,使肾小球硬化。本文就TRPC6的结构和功能以及与肾脏相关疾病的关系的研究进展作一综述。
出处 《国际泌尿系统杂志》 2021年第5期946-949,共4页 International Journal of Urology and Nephrology
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