超声引导下宫颈癌根治术的应用效果及对患者远期生存率的影响

Application effect of ultrasound-guided radical hysterectomy and its influence on long-term survival rate of patients

目的探讨超声引导下宫颈癌根治术的应用效果及对患者远期生存率的影响。方法选取本院2015年1月—2017年12月共收治的70例宫颈癌患者作为研究对象,将2016年7月—2017年12月纳入的患者作为观察组,2015年1月—2016年6月纳入的患者作为对照组,各35例,给予对照组患者常规腹腔镜根治术,给予观察组患者超声引导定位下腹腔镜宫颈癌根治术联合高强度凝聚超声热凝技术治疗。对比两组患者的治疗效果、远期生存率与复发率以及术后6个月、1年、2年、3年的FACT-G评分情况。结果两组疾病控制率对比无差异(97.14%vs 85.71%,P>0.05);观察组的治疗总有效率为高于对照组的(85.71%vs 60.00%,P<0.05);观察组和对照组患者1年生存率对比无差异(P>0.05),观察组2年、3年生存率高于对照组(P<0.05),观察组和对照组1年局部复发率对比无差异(P>0.05),观察组的2年、3年局部复发率低于对照组(P<0.05);观察组术后6个月、1年、2年、3年的FACT-G评分高于对照组(P<0.05)。结论应用超声引导定位下腹腔镜宫颈癌根治术联合高强度凝聚超声热凝技术治疗宫颈癌能够提升患者的治疗效果,减少疾病复发和提高远期生存率,提升患者的生存质量,值得临床应用推广。

Objective To investigate the application effect of ultrasound-guided radical hysterectomy for cervical cancer and its influence on the long-term survival rate of patients.Methods A total of 70 patients with cervical cancer admitted from January 2015 to December 2017 were selected as the research subjects,and the patients enrolled from July 2016 to December 2017 were selected as the observation group,patients from January 2015 to June 2016 as the control group,each with 35 cases.The control group was given conventional laparoscopic radical hysterectomy,and the observation group was given ultrasound-guided laparoscopic radical hysterectomy combined with high-intensity ultrasound coagulation technology.The treatment effect,long-term survival rate,recurrence rate and FACT-G scores 6 months,1 year,2 years and 3 years after operation were compared between the two groups.Results There were no significant differences in disease control rates between the two groups(97.14%vs 85.71%,P>0.05);the total effective rate of treatment in the observation group was higher than that in the control group(85.71%vs 60.00%,P<0.05).There was no significant difference in the 1-year survival rate between the observation and the control group(P>0.05).The 2-year and 3-year survival rate of the observation group were higher than that of the control group(P<0.05).There was no significant difference in comparison of 1-year local recurrence rate between the observation group and the control group(P>0.05).The 2-year and 3-year local recurrence rate of the observation group were lower than that of the control group(P<0.05).FACT-G scores in the observation group after surgery at 6 months,1 year,2 years,and 3 years were significantly higher than the control group(P<0.05).Conclusion The application of ultrasound-guided laparoscopic radical hysterectomy combined with high-intensity ultrasound coagulation in the treatment of cervical cancer can improve the treatment effect,reduce disease recurrence rate,increase long-term survival rate,and improve the quality of life of patients,which is worthy of clinical application and promotion.