异种脱细胞基质在腮腺手术中的应用分析

Analysis of heterogeneous acellular dermal matrix in parotidectomy

目的分析异种脱细胞基质在腮腺手术中的应用价值。方法分析97例在我科行腮腺手术的患者,其中观察组52例在腮腺全部或者部分切除后术腔植入异种脱细胞基质生物膜,另外对照组45例术后术腔未放置任何移植物以及其他自体组织填充于术腔,只给予逐层缝合,对比两组患者手术时间、术后引流总量、引流管拔除时间、术后疼痛程度以及涎腺瘘的发生率。结果两组患者手术时间无差异,观察组的术后引流总量、引流管拔除时间、术后疼痛程度以及术后涎腺瘘的发生率均少于对照组。结论异种脱细胞基质置入腮腺术后术腔内,可减少术腔引流管放置的时间,减轻患者术后的不适感,降低涎腺瘘的发生率,病人可获益。

Objective To evaluate the effect of heterogeneous acellular dermal matrix in parotidectomy.Methods Ninety-seven patients underwent parotidectomy in our hospital were divided into two groups,including 52 cases implanted biofilm of heterogeneous acellular dermal matrix in parotid gland cavity after total or partial resection as observation group,and 45 cases of postoperative cavitywere not filled graft or other autologous tissue,only given demixing suture as control group.The operation time,total amount of postoperative drainage,drainage tube removal time,postoperative pain degree and the sialosyrinx incidence were compared between two groups after surgery.Results There was no statistical difference in the operation time between the two groups.The total amount of postoperative drainage,the drainage tube removal time,the postoperative pain degree and sialosyrinx incidence in the observation group were all lower than those in the control group.Conclusion Heterogeneous acellular dermal matrix implantation is an effective method to reduce the time of placing the drainage tube in the operative cavity,relieve the postoperative discomfort,and reduce sialosyrinx incidence after parotidectomy,which can benefit the patients.