缺血性肠病的临床特征及影响因素分析

Analysis of clinical features and influencing factors of ischemic bowel disease

目的探讨缺血性肠病的临床特征及影响因素,为临床诊疗提供依据。方法选择54例缺血性肠病患者作为研究组,同期体检正常者30例作为对照组。收集两组研究对象的相关资料和相关血清生化指标,分析缺血性肠病的影响因素。结果研究组的脑血管病占比25.93%、房颤占比18.52%、糖尿病占比46.30%、体温(37.58±0.56)℃、心率(91.24±15.63)次/min、舒张压(98.63±9.27)mm Hg(1 mm Hg=0.133 kPa)、收缩压(150.58±15.39)mm Hg、腹胀占比33.33%、肠梗阻占比18.52%、便血占比37.04%、弥散性腹膜炎占比29.63%、年龄(78.35±11.26)岁、血钾(4.63±0.85)mmol/L、乳酸脱氢酶(692.58±105.63)mmol/L均高于对照组的0、3.33%、6.67%、(36.14±0.34)℃、(76.28±11.29)次/min、(61.36±8.25)mm Hg、(116.29±12.33)mm Hg、10.00%、0、0、0、(56.47±11.24)岁、(4.14±0.33)mmol/L、(375.26±85.11)mmol/L,血红蛋白(96.24±12.08)g/L、血钙(1.16±0.22)mmol/L均低于对照组的(136.82±20.59)g/L、(1.93±0.58)mmol/L,差异具有统计学意义(P<0.05)。两组研究对象的性别比较差异无统计学意义(P>0.05)。Logistic回归分析显示,脑血管病[OR=10.676,95%CI=(3.823,29.816)]、年龄[OR=3.486,95%CI=(1.145,10.615)]、糖尿病[OR=8.559,95%CI=(1.598,45.822)]、高血压[OR=12.679,95%CI=(2.565,65.622)]是缺血性肠病的独立危险因素(P<0.05)。结论脑血管病、年龄、糖尿病、高血压是缺血性肠病的独立危险因素,在治疗过程中需要积极治疗原发病,改善患者的预后,促使患者尽早康复。

Objective To discuss the clinical features and influencing factors of ischemic bowel disease to provide basis for clinical diagnosis and treatment.Methods There were 54 patients with ischemic bowel disease selected as the research group,and another 30 healthy subjects as the control group.The relevant data and relevant serum biochemical indicators of the two group were collected to analyze the influencing factors of ischemic bowel disease.Results In the research group,the cerebrovascular diseases accounted for 25.93%,atrial fibrillation accounted for 18.52%,diabetes accounted for 46.30%,body temperature was(37.58±0.56)℃,heart rate was(91.24±15.63)beats/min,diastolic blood pressure was(98.63±9.27)mm Hg(1 mm Hg=0.133 kPa),systolic blood pressure was(150.58±15.39)mm Hg,abdominal distension accounted for 33.33%,intestinal obstruction accounted for 18.52%,blood in stool accounted for 37.04%,diffuse peritonitis accounted for 29.63%,age was(78.35±11.26)years old,blood potassium was(4.63±0.85)mmol/L,lactate dehydrogenase was(692.58±105.63)mmol/L,which were all higher than 0,3.33%,6.67%,(36.14±0.34)℃,(76.28±11.29)beats/min,(61.36±8.25)mm Hg,(116.29±12.33)mm Hg,10.00%,0,0,0,(56.47±11.24)years old,(4.14±0.33)mmol/L,(375.26±85.11)mmol/L in the control group,and the hemoglobin(96.24±12.08)g/L and blood calcium(1.16±0.22)mmol/L were lower than(136.82±20.59)g/L and(1.93±0.58)mmol/L in the control group.All the difference was statistically significant(P<0.05).There was no statistically significant difference in the gender ratio between the two groups(P>0.05).Logistic regression analysis showed that cerebrovascular disease[OR=10.676,95%CI=(3.823,29.816)],age[OR=3.486,95%CI=(1.145,10.615)],diabetes[OR=8.559,95%CI=(1.598,45.822)],and hypertension[OR=12.679,95%CI=(2.565,65.622)]were independent risk factors for ischemic bowel disease(P<0.05).Conclusion Cerebrovascular disease,age,diabetes,and hypertension are independent risk factors for ischemic bowel disease,and active treatment of the primary disease is required in the treatment process to improve the prognosis and promote early recovery of patients.