宫颈上皮内瘤变行宫腔镜下宫颈锥形电切术治疗的效果观察

Observation on the effect of transcervical resection of cervical lesion under hysteroscope in the treatment of cervical intraepithelial neoplasia

目的探究宫颈上皮内瘤变(CIN)行宫腔镜下宫颈锥形电切术(TCRC)治疗的效果。方法50例CIN患者,根据手术方案的不同分为对照组与研究组,各25例。对照组给予宫颈冷刀锥形切除术(CKC)治疗,研究组给予TCRC治疗。比较两组手术情况、术后并发症发生情况及复发情况。结果研究组手术时间(10.68±3.12)min、切口愈合时间(35.76±5.74)d、住院时间(4.79±1.26)d短于对照组的(28.67±5.23)min、(48.56±7.45)d、(7.85±2.15)d,术中出血量(15.34±3.56)ml、医疗费用(1589.67±216.57)元少于对照组的(27.54±5.42)ml、(4562.58±453.87)元,差异均有统计学意义(P<0.05)。研究组并发症总发生率为4.00%,低于对照组的24.00%,差异有统计学意义(P<0.05);研究组复发率为0,低于对照组的16.00%,差异有统计学意义(P<0.05)。结论TCRC治疗CIN效果显著,具有手术时间短、术中出血少、医疗费用低的优势,能够有效切除病变组织,术后并发症少,复发率较低,安全可靠。

Objective To investigate the effect of transcervical resection of cervical lesion(TCRC)under hysteroscope in the treatment of cervical intraepithelial neoplasia(CIN).Methods A total of 50 patients with CIN were divided into control group and research group according to different surgical schemes,with 25 cases in each group.The control group was treated with cold knife conization(CKC),and the research group was treated with TCRC.The surgical indicators,postoperative complications,and recurrence status were compared between the two groups.Results The operation time(10.68±3.12)min,incision healing time(35.76±5.74)d,and hospitalization time(4.79±1.26)d in the research group were shorter than(28.67±5.23)min,(48.56±7.45)d,and(7.85±2.15)d in the control group,and the intraoperative blood loss(15.34±3.56)ml and medical cost(1589.67±216.57)yuan was less than(27.54±5.42)ml and(4562.58±453.87)in the control group.All the differences were statistically significant(P<0.05).The total complication rates in the research group was 4.00%,which was lower than 24.00%in the control group,and the difference was statistically significant(P<0.05).The recurrence rate of the research group was 0,which was lower than 16.00%of the control group,and the difference was statistically significant(P<0.05).Conclusion TCRC is effective in the treatment of CIN,and it has the advantages of short operation time,less intraoperative blood loss,low medical costs.It can effectively remove the diseased tissue,with less postoperative complications,low recurrence rate,and is safe and reliable.