食管微生态与食管疾病

The esophageal microbiome and esophageal disease

随着高通量测序和宏基因组学的兴起,食管微生态正成为一个热点研究领域。已有不少研究表明,正常食管中定植着复杂的微生物菌群,其组成伴随着食管疾病的进展而发生变化。本文将概述食管正常生理和疾病状态下的微生态特征,对于进一步探究食管微生态与食管疾病发病机制及诊疗策略提供借鉴。

With the rise of high-throughput sequencing and metagenomics,the esophageal microbiome is becoming a hot research field. Numerous studies have shown that complex microbial flora is colonized in esophagus,and its composition changes with the occurrence and development of esophageal diseases. This article will summarize the microbiological characteristics of the esophagus under the normal physiology and disease state,and provide reference significance for further exploring the potential mechanism,diagnosis and treatment of esophageal diseases.