地佐辛复合丙泊酚对患者全麻手术后苏醒期躁动情况及镇痛效果的影响

Influence of Dezocine Combined with Propofol on Restlessness during Awakening Period of Patients after General Anesthesia Surgery and the Analgesic Effect

目的分析地佐辛复合丙泊酚对患者全麻手术后苏醒期躁动情况及镇痛效果的影响。方法将2018年6月至2020年5月在我院行全麻手术的72例患者随机分为两组各36例。参照组静注地佐辛复合芬太尼,研究组静注地佐辛复合丙泊酚,对比两组的镇痛效果、苏醒期躁动情况、临床指标及不良反应发生率。结果研究组的VAS、SAS评分低于参照组(P<0.05)。研究组的睁眼时间、拔管时间短于参照组,拔管时HR、MAP低于参照组(P<0.05)。两组的不良反应发生率比较差异无统计学意义(P>0.05)。结论地佐辛复合丙泊酚可有效提高全麻手术患者的镇痛效果,减轻术后苏醒期躁动,缩短睁眼时间、拔管时间,稳定其拔管时HR、MAP,麻醉安全性较高。

Objective To analyze the influence of dezocine combined with propofol on restlessness during awakening period of patients after general anesthesia surgery and the analgesic effect.Methods 72 patients undergoing general anesthesia surgery in our hospital from June 2018 to May 2020 were randomly divided into two groups,with 36 cases in each group.The reference group received intravenous injection of dezocine combined with fentanyl,and the study group received intravenous injection of dezocine combined with propofol.The analgesic effect,restlessness during awakening period,clinical indicators and incidence of adverse reactions were compared between the two groups.Results The VAS and SAS scores of the study group were lower than those of the reference group(P<0.05).The eye opening time and extubation time of of the study group were shorter than those of the reference group,and the HR and MAP at extubation were lower than those of the reference group(P<0.05).No statistical difference was found in the incidence of adverse reactions between the two groups(P>0.05).Conclusions Dezocine combined with propofol can effectively improve the analgesic effect of patients after general anesthesia surgery,reduce postoperative restlessness during awakening period,shorten the eye opening time and extubation time,and stabilize the HR and MAP at extubation,with higher anesthesia safety.