孟河名医贺季衡《指禅医案·调经门》用药规律探析

Analysis on medication rules of Menstrual Diseases in Zhichan Medical Cases from Menghe famous doctor He Jiheng

目的基于古今医案云平台分析《指禅医案·调经门》药物规律,为临床治疗月经病提供参考。方法筛录《指禅医案·调经门》中有效医案用方,创建数据库,导入古今医案云平台,采用软件进行单味药物频次分析、关联分析、中药属性、聚类分析等研究贺季衡调经用药规律和特点。结果共录入调经门有效处方258首,涉及中药167味,使用频次≥70次的中药有15味,其中当归(249次)为应用最多的中药;药物主归于肝、脾经;主要功效为调经止痛、润肠通便、补血活血;药物关联分析同现频次最高的药物搭配为当归-白芍;聚类分析得到3组聚类方皆为临床上调经常用方。结论贺季衡在调经治疗中重视养血益气、疏肝健脾,将理气血和调肝脾两法贯彻始终。

Objective To analyze medication rules of Menstrual Diseases in Zhichan Medical Cases based on ancient and modern medical record cloud platform,and provide reference for clinical treatment of menstrual diseases.Methods The effective medical records of Menstrual Diseases in Zhichan Medical Cases were screened and recorded,database was created and imported into ancient and modern medical records cloud platform.The frequency analysis of single drug,correlation analysis,traditional Chinese medicine attribute and cluster analysis were carried out by software to study rules and characteristics of He Jiheng’s menstrual regulation drugs.Results A total of 258 effective prescriptions of menstrual diseases were entered,involving 167 traditional Chinese medicines.Fifteen traditional Chinese medicines were used more than 70 times,of which Angelicae Sinensis Radix(249 times)was the most used traditional Chinese medicine.Drugs were mainly attributed to liver and spleen channels.The main effects were regulating menstruation and relieving pain,moistening intestines and defecating,tonifying blood and activating blood circulation.The drug combination with the highest frequency of drug association analysis was Angelicae Sinensis Radix-Paeoniae Radix Alba.Cluster analysis showed that the three groups of cluster prescriptions were frequently used in clinical practice.Conclusion He Jiheng pays attention to nourishing blood and qi,soothing liver and strengthening spleen in the treatment of menorrhagia,and implements two methods of regulating qi and blood and regulating liver and spleen from beginning to end.