期刊文献+

脂质体吸入剂研究进展

Research on Liposome Inhalation
下载PDF
导出
摘要 脂质体作为一类常见的代表性纳米制剂,具有较高的技术难度和行业准入壁垒,在高端制剂市场中所占比重较大。在抗病毒、抗超级细菌、抗真菌感染等领域,亟需开发吸入剂新品。开发和应用脂质体吸入剂核心技术对国内药企而言,既是重大的发展机遇,也是弯道超车提升产业水平的重要路径。在后新冠疫情时代如何在适合的赛道开发差异化的高端制剂,值得深思。 Liposomes,as a kind of common representative nano agents,have high technical difficulty and industry access barriers,and occupy a large proportion in the high-end pharmaceutical market.At the same time,inhalation pharmaceutical formulation in the field of anti-virus,anti-super-bacteria,fungal infection,also need to develop new products.The project development of dosage forms such as inhaled liposomes is also a major development opportunity for domestic pharmaceutical enterprises,and it is also an important way to improve their industrial level.It is worth pondering how to develop differentiated high-end complex pharmaceutical formulation in an appropriate way in the post COVID-19 epidemic era.
作者 赵海峰 沈晔茜 ZHAO Hai-feng;SHEN Ye-qian(Nanjing Youxi Pharmaceutical Technology Co., Ltd., Nanjing 211166, Jiangsu, China;Jiangsu Vocational Institute of Commerce, Nanjing 211168, Jiangsu, China)
出处 《江苏调味副食品》 2021年第3期6-9,共4页 Jiangsu Condiment and Subsidiary Food
关键词 脂质体 吸入剂 靶向性 差异化开发 市场效益 liposome inhalant formulation targeting differentiated development market benefits
  • 相关文献

参考文献6

二级参考文献86

  • 1黄寿吾,付朝宏,杨五彪,李惜光,陶元器,杨春雷.脂质体肝素透皮吸收的初步观察[J].中国生化药物杂志,1996,17(1):8-11. 被引量:9
  • 2[1]Vaage J,Mayhew E,Lasic D.Therapy of primary and metastatic mouse mammary carcinomas with doxorubicin encapsulated in long circulating liposomes[J].Int J Cancer,1992,51(6):942-948
  • 3[2]Russo D,Piccaluga PP,Michieli M.Liposomal daunorubicin (DaunoXome) for treatment of poor-risk acute leukemia.Ann Hematol,2002,81 (8):462-466
  • 4[4]Overmoyer B,Silverman P,Holder LW.Pegylated liposomal Doxorubicin and cyclophosphamide as first-line therapy for patients with metastatic or recurrent breast cancer.Clin Breast Cancer,2005,6 (2):150-157
  • 5[5]Krown SE,Northfelt DW,Osoba D.Use of liposomal anthracyclines in Kaposi's sarcoma.Semin Oncol,2004,31(6 Suppl 13):36-52
  • 6[6]Mross K,Niemann B,Massing U.Pharmacokinetics of liposomal doxorubicin (TLC-D99; Myocet) in patients with solid tumors:an open-label,single-dose study.Cancer Chemother Pharmacol,2004,54(6):514-24
  • 7[7]Janssen AP,Schiffelers RM,ten Hagen TL.Peptide-tsrgeted PEG-liposomes in anti-angiogenic therapy.Int J Pharm,2003,254(1):55-58
  • 8[8]Schiffelers RM,Koning GA,ten Hagen TL.Anti-tumor efficacy of tumor vasculature-targeted liposomal doxorubicin.J Control Release,2003,91 (1-2):115-122
  • 9[9]Koning GA,Fretz MM,Woroniecka U.Targeting liposomes to tumor endothelial cells for neutron capture therapy.Appl Radiat Isot,2004,61 (5):963-967
  • 10[10]Dubey PK,Mishra V,Jain S.Liposomes modified with cyclic RGD peptide for tumor targeting.J Drug Target,2004,12(5):257-64

共引文献38

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部