雷贝拉唑联合替普瑞酮治疗慢性胃炎45例疗效观察

Observation on the curative effect of rabeprazole combined with teprenone in the treatment of 45 cases of chronic gastritis

目的:探究雷贝拉唑联合替普瑞酮治疗慢性胃炎的临床效果。方法:2018年1月-2019年1月收治慢性胃炎患者90例,随机分为两组,各45例。对照组使用替普瑞酮治疗;观察组在替普瑞酮基础上加用雷贝拉唑治疗。比较两组患者临床症状改善效果、不良反应发生情况及治疗总有效率。结果:观察组患者腹胀、上腹疼痛及反酸等症状消失时间均明显短于对照组,差异有统计学意义(P<0.05);观察组治疗总有效率显著高于对照组,差异有统计学意义(P<0.05);两组患者均未出现明显不良反应情况。结论:雷贝拉唑联合替普瑞酮治疗慢性胃炎,能快速改善患者临床症状,修复胃黏膜,治疗效果显著,且未见明显不良反应。

Objective:To explore the clinical effect of rabeprazole combined with teprenone in the treatment of chronic gastritis.Methods:From January 2018 to January 2019,90 patients with chronic gastritis were selected and randomly divided into two groups with 45 cases in each group.The control group was treated with teprenone.The observation group was treated with rabeprazole in addition to teprenone.The improvement effect of clinical symptoms,the incidence of adverse reactions and the total effective rate of treatment were compared between the two groups.Results:The disappearance time of abdominal distension,epigastric pain and acid reflux in the observation group was significantly shorter than the control group,the differences were statistically significant(P<0.05).The total effective rate of the observation group was significantly higher than the control group,the difference was statistically significant(P<0.05).There were no obvious adverse reactions in 2 groups.Conclusion:Rabeprazole combined with teprenone in the treatment of chronic gastritis can quickly improve the clinical symptoms of patients and repair the gastric mucosa,with significant therapeutic effects,and no obvious adverse reactions.