双相情感障碍患者伴焦虑症状的相关因素分析

Analysis of Related Factors of Anxiety Symptoms in Patients with Bipolar Disorder

目的:探讨双相情感障碍患者伴焦虑症状的相关因素。方法:选取笔者所在医院2019年4月-2021年4月收治的80例双相情感障碍患者,按照是否伴焦虑症状将其分为伴焦虑症状组(22例)和未伴焦虑症状组(58例)。采用多因素非条件Logistic回归分析双相情感障碍患者伴焦虑症状的影响因素。结果:单因素分析显示,伴焦虑症状组女性、抑郁发作频繁、有诱因发作、有周期性或季节性特点的患者占比均高于未伴焦虑症状组,伴焦虑症状组年龄大于未伴焦虑症状组,平均首次发病年龄小于未伴焦虑症状组,平均既往发病次数多于未伴焦虑症状组(P<0.05);多因素非条件Logistic回归分析显示,抑郁发作频繁、有诱因发作均为双相情感障碍患者伴焦虑症状的危险因素(OR=1.047、1.182,P<0.05)。结论:抑郁发作频繁、有诱因发作均为双相情感障碍患者伴焦虑症状的危险因素,早期识别危险因素,采取有效措施治疗双相障碍患者的焦虑症状,有利于提高临床疗效,改善患者的生活质量。

Objective:To investigate the related factors of anxiety symptoms in patients with bipolar disorder.Method:A total of 80 patients with bipolar disorder who were admitted in our hospital from April 2019 to April 2021 were selected.They were divided into the with anxiety symptoms group(22 cases)and the without anxiety symptoms group(58 cases)according to whether they had anxiety symptoms.Multivariate non-conditional Logistic regression was used to analyze the influencing factors of anxiety symptoms in patients with bipolar disorder.Result:Univariate analysis showed that the proportion of female,patients with frequent depressive episodes,provoked episodes,and periodic or seasonal characteristics in the with anxiety symptoms group were higher than those in the without anxiety symptoms group.The age of the with anxiety symptoms group was higher than that of the without anxiety symptoms group,the average age of first onset was lower than that of the without anxiety symptoms group,and the average number of previous onset was higher than that of the without anxiety symptoms group(P<0.05).Multivariate non-conditional Logistic regression analysis showed that frequent depressive episodes and provoked episodes were risk factors of anxiety symptoms in patients with bipolar disorder(OR=1.047,1.182,P<0.05).Conclusion:Frequent depressive episodes and provoked episodes are risk factors of anxiety symptoms in patients with bipolar disorder.Early identification of risk factors and implementation of effective measures to treat anxiety symptoms in patients with bipolar disorder are beneficial to improve clinical efficacy and improve the quality of life of patients.