抗反流药物治疗对支气管哮喘合并胃食管反流病患者的效果观察

Effect of Anti-reflux Medication Treatment in Patients with Asthma Complicated with Gastroesophageal Reflux Disease

目的:探讨抗反流药物治疗对支气管哮喘合并胃食管反流病(gastroesophageal reflux disease,GERD)患者哮喘症状及肺功能的影响。方法:选取2016年3月-2019年10月笔者所在医院门诊就诊的67例支气管哮喘合并GERD患者,根据是否应用抗反流药物治疗将其分为治疗组(n=34)及对照组(n=33)。比较两组支气管哮喘控制水平及肺功能。结果:治疗后,治疗组ACT评分高于对照组,差异有统计学意义(P<0.05)。治疗后,治疗组FEV1占预计值百分比及PEF占预计值百分比均高于对照组,差异有统计学意义(P<0.05)。结论:抗反流药物治疗可改善支气管哮喘合并GERD患者的哮喘症状及肺功能。

Objective:To explore the effect of anti-reflux medication treatment on the asthma symptoms and lung function in patients with asthma complicated with gastroesophageal reflux disease (GERD).Method:A total of 67 patients with asthma complicated with GERD in the outpatient department of our hospital from March 2016 to October 2019 were selected and divided into the treatment group (n=34) and the control group (n=33) according to whether anti-reflux medication were used.The control level of asthma and lung function were compared between the two groups.Result:After treatment,ACT score of the treatment group was higher than that of the control group,and the difference was statistically significant (P<0.05).After treatment,the percentage of FEV1 and PEF in the estimated value in the treatment group were both higher than those in the control group,and the differences were statistically significant (P<0.05).Conclusion:Anti-reflux medication treatment can improve asthma symptoms and lung function in patients with asthma complicated with GERD.