糖尿病足溃疡感染给予全身抗菌药物治疗的效果

Effect of Systemic Antibiotics on Diabetic Foot Ulcer Infection

目的:分析糖尿病足溃疡感染全身抗菌药物治疗效果。方法:随机抽选2017年1月-2020年9月本院接收的220例糖尿病足溃疡感染患者,按照系统抽样法分组,各110例。对照组实施常规治疗,观察组在常规治疗的基础上对于中、重度感染的患者增加全身抗菌药物治疗,对两组治疗效果进行对比分析。结果:观察组治疗总有效率为94.55%,高于对照组的86.36%,差异有统计学意义(P<0.05);治疗前两组C反应蛋白、空腹血糖比较差异无统计学意义(P>0.05);治疗后,观察组C反应蛋白、空腹血糖较对照组低,差异有统计学意义(P<0.05);观察组治疗后溃疡面积及住院时间优于对照组,差异有统计学意义(P<0.05)。结论:糖尿病足溃疡感染临床治疗过程中,全身抗菌药物的应用,不仅可以减小溃疡范围,改善空腹血糖及C反应蛋白,而且有助于患者治疗效果提高,减少住院时间,值得临床进一步采纳与推广。

Objective:To analyze the therapeutic effect of systemic antibiotics on diabetic foot ulcer infection.Method:A total of 220 patients with diabetic foot ulcer infection in our hospital were randomly selected from January 2017 to September 2020,and were divided into two groups according to the systematic sampling method,110 cases in each group.The control group received routine treatment,the observation group added systemic antibiotics therapy to the patients with medium and key infections on the basis of routine treatment.The treatment effects of the two groups were compared and analyzed.Result:The total effective rate of the observation group was 94.55%,which was higher than 86.36% of the control group,the difference was statistically significant (P<0.05).There were no significant differences in C-reactive protein,fasting blood glucose between the two groups before treatment (P>0.05);after treatment,the C-reactive protein,fasting blood glucose in the observation group were lower than those in the control group,and the differences were statistically significant (P<0.05).The ulcer area after treatment and length of hospital stay in the observation group were better than those in the control group,and the differences were statistically significant (P<0.05).Conclusion:In the clinical treatment of diabetic foot ulcer infection,the application of systemic antibiotics can not only reduce the scope of ulcer,improve fasting blood glucose and C-reactive protein,but also help to improve the treatment effect and reduce the length of hospital stay,which is worthy of further clinical adoption and promotion.