非酒精性脂肪肝证候分布规律探析

Analysis on the Distribution Regularity of Nonalcoholic Fatty Liver Disease

目的对现有数据库近5年的数据资料进行挖掘,探讨非酒精性脂肪肝证候的分布特点,为临床辨证治疗提供参考依据。方法在中国知网、维普、万方等数据库检索2015年1月-2019年12月有关研究非酒精性脂肪肝证候的文献资料,筛选出符合纳入标准的文献并进行频数统计分析。结果非酒精性脂肪肝的主要证候为湿热内蕴证、肝郁脾虚证、痰湿内阻证、痰瘀互结证、湿浊内停证、肝郁气滞证;病位证素为肝、脾、肾,病性证素主要为湿、气滞、热、痰、气虚、血瘀等。结论非酒精性脂肪肝的证候分布以实证居多,肝、脾、肾为主要病变部位,湿、气滞、热、痰、气虚、血瘀是非酒精性脂肪肝的病理产物,因此临床上治疗非酒精性脂肪肝应以祛邪为主,兼顾扶正,可以采取清热利湿、疏肝健脾、运脾利湿、化痰祛瘀等治法。

Objective In order to provide reference for the treatment of nonalcoholic fatty liver disease(NAFLD)based on clinical syndrome differentiation,the distribution characteristics of non-alcoholic fatty liver syndrome were explored by mining the data from the existing database in recent 5 years.Methods Literature on the study of non-alcoholic fatty liver syndrome from January 2015 to December 2019 was searched in the CNKI,VIP,Wanfang database,and those that met the inclusion criteria were screened out for frequency statistical analysis.Results The main syndromes of NAFLD are dampness-heat intrinsic syndrome of liver stagnation and spleen deficiency syndrome of phlegm-dampness internal obstruction syndrome of phlegm-dampness internal stasis syndrome of phlegm-dampness internal stagnation syndrome of liver stagnation and qi stagnation syndrome.The syndromes were liver,spleen and kidney,and the syndromes were dampened qi stagnation,heat phlegm,qi deficiency and blood stasis.Conclusion The syndromes and syndromes of NAFLD are mainly positivistic,the liver,spleen and kidney are the main pathological sites,and the heat phlegm of dampened qi stagnation and qi deficiency and blood stasis are the pathological products of NAFLD.Therefore,in the clinical treatment of non-alcoholic fatty liver,it is necessary to focus on dispelling pathogenic factors,take into account the strengthening of the body,and adopt the treatment methods of clearing heat,promoting dampness,soothing liver,strengthening spleen,removing phlegm,removing blood stasis,etc.