小建中汤治疗慢性心力衰竭合并便秘临床观察

Clinical Observation on Xiaojianzhong Decoction in the Treatment of Chronic Heart Failure with Constipation

目的探讨加味小建中汤治疗慢性心力衰竭合并便秘的临床疗效。方法选取2019年1月-2020年1月中国医科大学附属盛京医院收治的70例慢性心力衰竭合并便秘患者作为研究对象,随机分为对照组和试验组,每组35例。对照组予以常规疗法预防便秘,必要时应用开塞露纳肛或温水送服聚乙二醇4000散,试验组在对照组的基础上使用加味小建中汤治疗。比较2组的治疗效果、便秘证候积分、首次排便时间及不良反应总发生率。结果试验组的治疗总有效率为97.14%(34/35),高于对照组的65.71%(23/35),差异有统计学意义(P<0.05);试验组治疗后的便秘证候积分低于对照组,差异有统计学意义(P<0.05);试验组的首次排便时间短于对照组,差异有统计学意义(P<0.05);试验组的不良反应总发生率低于对照组,差异有统计学意义(P<0.05)。结论加味小建中汤治疗慢性心力衰竭合并便秘的临床效果显著,在临床上值得推广应用。

Objective To explore the clinical effect of modified Xiaojianzhong decoction on chronic heart failure patients with constipation.Methods A total of 70 patients with chronic heart failure complicated with constipation admitted to Shengjing Hospital affiliated to China Medical University from January 2019 to January 2020 were selected as the study subjects and randomly divided into control group and experimental group,with 35 patients in each group.The control group was given conventional therapy to prevent constipation,and polyethylene glycol 4000 powder was taken with kaiseruna anus or warm water when necessary.The experimental group was treated with flavored Xiaojianzhong decoction on the basis of the control group.The treatment effect,constipation syndrome score,first defecation time and total incidence of adverse reactions were compared between the two groups.Results The total effective rate in experimental group was 97.14%(34/35),which was higher than 65.71%(23/35)in control group,and the difference was statistically significant(P<0.05).The score of constipation syndrome in the experimental group was lower than that in the control group,and the difference was statistically significant(P<0.05).The time of first defecation in experimental group was shorter than that in control group,and the difference was statistically significant(P<0.05).The total incidence of adverse reactionin experimental group was lower than that in control group,and the difference was statistically significant(P<0.05).Conclusion The clinical effect of Xiaojianzhong decoction in the treatment of chronic heart failure with constipation is significant,which is worth popularizing.