山东一规模化驴场主要细菌病的流行病学与防控研究

Study on Epidemiology and Control of Major Bacterial Diseases in a Large-Scale Donkey Farm in Shandong Province

2018—2020年对山东一规模化驴场进行了系统的流行病学研究,发现目前驴养殖最大的病害是细菌病,其中大肠杆菌感染最为严重,阳性率显著高于其他细菌,并发现了缺失K88、K99等毒力基因的大肠杆菌菌株。通过不同防治方案的效果比对,发现短小芽孢杆菌与植物乳杆菌等驴源肠道的益生菌对治疗与调理细菌导致的腹泻效果显著。本研究明晰了集约化驴场细菌感染和流行状况,可为驴场细菌病的科学防控提供策略。

The systematic epidemiological study of a large-scale donkey farm in Shandong Province was conducted during 2018-2020. It was found that the leading disease of donkey was bacterial disease, in which, Escherichia coli infection was the most serious with the positive rate significantly higher than that of the other bacteria. The E. coli strains lacking K88, K99 and other virulence genes were also found. By comparing the effects of different control schemes, it was found that probiotics from donkey intestines such as Bacillus brevis and Lactobacillus plantarum were significantly effective on treating and regulating diarrhea caused by bacteria. The results of this study clarified the bacterial infection and epidemic situation in the intensive donkey farms and provided scientific prevention and control strategies.