摘要
The phenomenon and potential mechanisms of trans-kingdom RNA silencing(or RNA interference,RNAi)are among the most exciting topics in science today.Based on trans-kingdom RNAi,host-induced gene silencing(HIGS)has been widely applied to create crops with resistance to various pests and pathogens,overcoming the limitations of resistant cultivars.However,a lack of transformation technology in many crops limits the application of HIGS.Here,we describe the various fates of trans-kingdom RNAs in recipient organisms.Based on the assumption that small RNAs can be transferred between the host and its microbiome or among microbiome members,we propose a possible alternative strategy for plant protection against pathogens without the need for crop genetic modification.
基金
supported by the National Natural Science Foundation of China(no.31730078).