行政事业单位人员高尿酸血症与代谢综合征的相关性分析

Correlation Analysis of Hyperuricemia and Metabolic Syndrome in Administrative Institutions

目的:研究和分析行政事业单位人员中高尿酸血症(HUA)与代谢综合征(MS)的相关性。方法:选取泸州市行政事业单位721例确诊为高尿酸血症的人群(男性高于416μmol/L、女性高于357μmol/L),作为研究对象,该人群曾于2019年1~12月在泸州市中医医院进行健康体检。同时根据代谢综合征诊断标准对所有患者进行诊断分析,并且采用Logistic多因素回归分析高尿酸血症与代谢综合征的相关性,其中代谢综合征相关因素包括了性别、腹围、血压(收缩压、舒张压)、血糖、甘油三酯、高密度脂蛋白胆固醇等。结果:根据多因素结果分析显示,腹围、血压(收缩压、舒张压)、血糖、甘油三酯与高尿酸血症水平均呈正相关水平,高密度脂蛋白胆固醇与高尿酸血症水平均呈负相关水平,可见高尿酸血症是代谢综合征的独立危险因素,且在高尿酸血症患者中,男性尿酸浓度明显高于女性,差异有统计学意义(P<0.05),但是不同性别患者的代谢综合征检出率差异不显著,无统计学意义(P>0.05)。结论:行政事业单位人员中高尿酸血症与代谢综合征具有较高的相关性。

Objective:to study and analyze the correlation between hyperuricemia(HUA)and metabolic syndrome(MS)in administrative institutions.Methods:721 patients diagnosed with hyperuricemia in administrative institutions of Luzhou City were selected(men above 416μmol/L、women above 357μmol/L),As a subject,The crowd had a health examination in Luzhou traditional Chinese Medicine Hospital from January 2019 to December 2019.At the same time,according to the diagnostic criteria of metabolic syndrome,And Logistic multivariate regression was used to analyze the correlation between hyperuricemia and metabolic syndrome,The related factors of metabolic syndrome include sex,abdominal circumference,blood pressure(systolic blood pressure,diastolic blood pressure),blood sugar,triglyceride,high density lipoprotein cholesterol and so on.Results:According to the multi-factor analysis,The levels of abdominal circumference,blood pressure(systolic blood pressure,diastolic blood pressure),blood glucose,triglyceride and hyperuricemia were positively correlated,High density lipoprotein cholesterol and hyperuricemia levels were negatively correlated,Hyperuricemia is an independent risk factor for metabolic syndrome,And in patients with hyperuricemia,Uric acid levels were significantly higher in men than in women,difference was statistically significant(P<0.05),But there was no significant difference in the detection rate of metabolic syndrome between the sexes,had no statistical significance(P>0.05).Conclusion:There is a high correlation between hyperuricemia and metabolic syndrome.