摘要
孕妇妊娠期用药不当可能具有导致胎儿发生畸形的风险。妊娠期药物致畸风险咨询服务在保障母胎用药安全、减少出生缺陷方面发挥重要作用。目前,我国部分医疗机构已开展妊娠期药物致畸风险咨询服务,但是尚未制定涉及该项服务的相关技术规范。四川大学华西第二医院全国妇幼卫生监测办公室/中国出生缺陷监测中心,联合国内多家三级甲等医疗机构的产科、儿科、药剂科等多学科专家,共同制定《妊娠期药物致畸风险咨询技术规范》。该技术规范规定了妊娠期药物致畸风险咨询服务的定义、原则、流程、服务方式等内容,旨在指导我国医疗机构规范开展该项咨询服务工作,提升服务水平,保障母胎用药安全。
Improper use of drugs by pregnant women during pregnancy may lead to fetal malformations.Counseling service on the risk of drug teratogenicity during pregnancy plays an important role in ensuring the safety of maternal and fetal medication and reducing birth defects.At present,some medical institutions in China have carried out counseling service on the risk of drug teratogenicity during pregnancy,but there is no relevant technical specification of the service.The Technical Specification for Consultation on the Risk of Drug Teratogenicity During Pregnancy has been jointly formulated by National Office for Maternal and Child Health Surveillance of China/National Center for Birth Defects Monitoring of China and multidisciplinary experts in department of obstetrics,pediatrics,pharmacy,etc.from Grade 3A medical institutions in China.The technical specification stipulates the definition,principle,process and service mode of drug teratogenic risk consultation service during pregnancy,in order to guide China′s medical institutions to standardize the counseling service,improve the service level,and ensure the safety of maternal and fetal medication.
作者
陶晶
李小洪
谭曦
陈力
尹爱华
王和
赵扬玉
杨勇
张欣文
张晓辉
王雪燕
陈敦金
杜娟
陈素华
蒋小青
张国英
李力
张岩
顾锦华
李芬
谢兰
赵娟娟
张春红
朱军
Tao Jing;Li Xiaohong;Tan Xi;Chen Li;Yin Aihua;Wang He;Zhao Yangyu;Yang Yong;Zhang Xinwen;Zhang Xiaohui;Wang Xueyan;Chen Dunjin;Du Juan;Chen Suhua;Jiang Xiaoqing;Zhang Guoying;Li Li;Zhang Yan;Gu Jinhua;Li Fen;Xie Lan;Zhao Juanjuan;Zhang Chunhong;Zhu Jun(National Office for Maternal and Child Health Surveillance of China/National Center for Birth Defects Monitoring of China,West China Second University Hospital,Sichuan University,Chengdu 610041,Sichuan Province,China;Key Laboratory of Birth Defects and Related Diseases of Women and Children(Sichuan University),Ministry of Education,West China Second University Hospital,Sichuan University,Chengdu 610041,Sichuan Province,China;Department of Obstetrics and Gynecology,West China Second University Hospital,Sichuan University,Chengdu 610041,Sichuan Province,China;Department of Pharmacy,West China Second University Hospital,Sichuan University,Chengdu 610041,Sichuan Province,China;Guangdong Maternal and Child Health Hospital,Guangzhou 510010,Guangdong Province,China;Prenatal Diagnostic Center,West China Second University Hospital,Sichuan University,Chengdu 610041,Sichuan Province,China;Peking University Third Hospital,Beijing 100191,China;Sichuan Academy of Medical Sciences·Sichuan Provincial People′s Hospital,Chengdu 610072,Sichuan Province,China;Xi′an People′s Hospital/Xi′an Fourth Hospital,Xi′an 710061,Shaanxi Province,China;Women′s Hospital School of Medicine Zhejiang University,Hangzhou 310006,Zhejiang Province,China;Chongqing Health Center for Women and Children,Chongqing 400010,China;Third Affiliated Hospital of Guangzhou Medical University,Guangzhou 510150,Guangdong Province,China;Maternal and Child Health Care Hospital of Guangxi Zhuang Autonomous Region,Nanning 530003,Guangxi Zhuang Autonomous Region,China;Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology,Wuhan 430030,Hubei Province,China;Jiangsu Women and Children Health Hospital,Nanjing 210036,Jiangsu Province,China;Army Medical Center for People′s Liberation Army,Chongqing 400042,China;Wuxi Maternal and Child Health Hospital,Wuxi 214000,Jiangsu Province,China;Maternity and Child Health Care Hospital Affiliated to Nantong University,Nantong 226000,Jiangsu Province,China;First Affiliated Hospital of Xi′an Jiaotong University,Xi′an 710004,Shaanxi Province,China;Urumqi Maternal and Child Health Hospital,Urumqi 830000,Xinjiang Uygur Autonomous Region,China;First Affiliated Hospital of Wenzhou Medical University,Wenzhou 325000,Zhejiang Province,China)
出处
《中华妇幼临床医学杂志（电子版）》
CAS
2021年第4期393-401,共9页
Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition)
基金
国家重点研发计划专项项目(2018YFC1002201)
四川省科技计划重点研发项目(2019YFS0530)。
关键词
妊娠
药物毒性
畸形
药物性
药物副反应报告系统
指示性咨询
Pregnancy
Drug toxicity
Abnormalities,drug-induced
Adverse drug reaction reporting systems
Directive counseling
