1970—2015年广东省中山市儿童恶性肿瘤发病分析

Analysis of Childhood Cancer Incidence in Zhongshan of Guangdong Province, 1970—2015

[目的]分析广东省中山市儿童恶性肿瘤发病资料。[方法]收集、整理1970—2015年中山市户籍儿童恶性肿瘤发病资料,统计研究其发病例数、发病粗率、年龄标化率和年龄别率等指标。采用2000年全国人口普查标准人口年龄构成和Segi’s世界标准人口年龄构成分别计算中标率和世标率。[结果] 1970—2015年,广东省中山市儿童恶性肿瘤发病1 131例,发病中标率和世标率分别为2.44/10万和2.29/10万。1~岁年龄组儿童发病率最高,0~岁组最低。不同时段年龄别发病模式有所不同。发病前5位的恶性肿瘤分别是白血病、脑部肿瘤、淋巴瘤、视网膜肿瘤和肾恶性肿瘤。1970—2015年期间发病率呈明显上升趋势,不同年龄组发病率也均上升,尤以0~岁和1~岁年龄组最明显。[结论] 1970—2015年广东省中山市儿童恶性肿瘤发病率明显上升,应加强儿童恶性肿瘤的防治工作。

[Purpose] To analyze the incidence of childhood cancers in Zhongshan City, 1970—2015. [Methods] The data of new cancer cases in children among Zhongshan registered residents in 1970—2015 were collected and the crude incidence rate was calculated. The age standardized rates adjusted by Chinese standard population in 2000(ASR-C) and world Segi’s standard population(ASR-W) were calculated and the age-specific incidence rate was also calculated. [Results]In 1970—2015, there were 1 131 new cases of childhood cancers in Zhongshan, with ASR-C of2.44/105 and ASR-W of 2.29/105. The highest age-specific incidence was in 1~ year group, while the lowest was in 0~ year group. Age-specific disease patterns varied in different period. Leukemia,brain cancer, lymphoma, retina cancer and kidney cancer were the top 5 cancers. During 1970—2015, incidence increased significantly, especially for the age groups of 0~ and 1~ year. [Conclusion] There was an increasing incidence trend of childhood cancers in Zhongshan in 1970—2015, control and prevention measures should be enhanced for childhood cancer.