摘要
In this paper,we propose a new algorithm to extend support vector machine(SVM)for binary classification to multicategory classification.The proposed method is based on a sequential binary classification algorithm.We first classify a target class by excluding the possibility of labeling as any other classes using a forward step of sequential SVM;we then exclude the already classified classes and repeat the same procedure for the remaining classes in a backward step.The proposed algorithm relies on SVM for each binary classification and utilizes only feasible data in each step;therefore,the method guarantees convergence and entails light computational burden.We prove Fisher consistency of the proposed forward–backward SVM(FB-SVM)and obtain a stochastic bound for the predicted misclassification rate.We conduct extensive simulations and analyze real-world data to demonstrate the superior performance of FB-SVM,for example,FB-SVM achieves a classification accuracy much higher than the current standard for predicting conversion from mild cognitive impairment to Alzheimer’s disease.
基金
This work is supported by NIH Grants R01GM124104,NS073671,NS082062,NUL1 RR025747
Alzheimer’s Disease Neuroimaging Initiative(ADNI)(U01 AG024904,DOD ADNI,W81XWH-12-2-0012),and a pilot award from the Gillings Innovation Lab at the University of North Carolina.The authors acknowledge the investigators within the ADNI who contributed to the design and implementation of ADNI.