探讨急性脑梗死患者血清胱抑素C、凝血功能检验的价值

The Value of Serocystatin C and Coagulation Function Test in Patients with Acute Cerebral Infarction

目的:分析和探究血清胱抑素C、凝血功能检验在急性脑梗死患者中的应用效果。方法:选取2018年7月~2020年6月某院收治的64例急性脑梗死患者和同期64例健康体检者开展研究,急性脑梗死患者设为观察组,健康体检者设为对照组,两组研究人员分别接受血清胱抑素C、凝血功能检验,并对比其检验结果。结果:以血清胱抑素C、血浆纤维蛋白为对比指标,对照组研究对象为(1.08±0.24)mg/L、(2.63±1.02)g/L,观察组患者为(1.53±0.26)mg/L、(3.05±1.11)g/L,两者相比较,观察组明显较高(P<0.05);血浆凝酶原时间、抗血凝酶-Ⅲ指标相比,观察组(15.38±3.49)、(66.54±18.59)显著低于对照组(22.09±6.25)、(83.27±18.11),数据存在对比意义(P<0.05);进展型急性脑梗死患者的血清胱抑素C(1.52±0.09)mg/L、血浆纤维蛋白(3.09±1.15)g/L指标与完全型急性脑梗死患者(1.47±0.08)mg/L、(2.53±1.02)g/L相比,明显较高(P<0.05);血浆凝酶原时间、抗血凝酶-Ⅲ指标相比,进展型急性脑梗死患者(15.48±3.82)、(67.30±19.28)显著低于完全型急性脑梗死患者(23.69±7.31)、(85.29±17.43)(P<0.05)。结论:在对急性脑梗死患者进行诊断的过程中,采取血清胱抑素C、凝血功能检验的临床效果较为显著,可较好的反映其病情变化程度,应用价值较高,值得进一步推广。

Objective:To analyze and explore the application effect of serocystatin C and coagulation function test in patients with acute cerebral infarction.Methods:64 cases of patients with acute cerebral infarction(study group)in a hospital from July 2018 to June 2020 and 64 health check-ups(control group)in the same period were selected and studied.Both groups of researchers were tested for serocystatin C and coagulation function,and the results were compared.Results:Taking serocystatin C and plasma fibrin as contrast indexes,the subjects in the control group were(1.08±0.24)mg/L and(2.63±1.02)g/L,while those in the observation group were(1.53±0.26)mg/L and(3.05±1.11)g/L,which were significantly higher in the observation group(P<0.05).The plasma prothrombin time and antithrombin-Ⅲindicators in the observation group were(15.38±3.49)and(66.54±18.59),which were significantly lower than(22.09±6.25)and(83.27±18.11)in the control group,and the difference was statistically significant(P<0.05).The serocystatin C and plasma fibrin in patients with advanced acute cerebral infarction were(1.52±0.09)mg/L and(3.09±1.15)g/L,which were significantly higher than(1.47±0.08)mg/L and(2.53±1.02)g/L in patients with complete acute cerebral infarction(P<0.05);The plasma prothrombin time and antithrombin-Ⅲindicators in patients with advanced acute cerebral infarction were(15.48±3.82)and(67.30±19.28),which were significantly lower than(23.69±7.31)and(85.29±17.43)in patients with complete acute cerebral infarction(P<0.05).Conclusion:In the process of diagnosis of patients with acute cerebral infarction,the clinical effect of serocystatin C and coagulation function test are relatively significant,which can better reflect the degree of disease change,has high application value,and is worthy of further promotion.