摘要
目的:分析和探究血清胱抑素C、凝血功能检验在急性脑梗死患者中的应用效果。方法:选取2018年7月~2020年6月某院收治的64例急性脑梗死患者和同期64例健康体检者开展研究,急性脑梗死患者设为观察组,健康体检者设为对照组,两组研究人员分别接受血清胱抑素C、凝血功能检验,并对比其检验结果。结果:以血清胱抑素C、血浆纤维蛋白为对比指标,对照组研究对象为(1.08±0.24)mg/L、(2.63±1.02)g/L,观察组患者为(1.53±0.26)mg/L、(3.05±1.11)g/L,两者相比较,观察组明显较高(P<0.05);血浆凝酶原时间、抗血凝酶-Ⅲ指标相比,观察组(15.38±3.49)、(66.54±18.59)显著低于对照组(22.09±6.25)、(83.27±18.11),数据存在对比意义(P<0.05);进展型急性脑梗死患者的血清胱抑素C(1.52±0.09)mg/L、血浆纤维蛋白(3.09±1.15)g/L指标与完全型急性脑梗死患者(1.47±0.08)mg/L、(2.53±1.02)g/L相比,明显较高(P<0.05);血浆凝酶原时间、抗血凝酶-Ⅲ指标相比,进展型急性脑梗死患者(15.48±3.82)、(67.30±19.28)显著低于完全型急性脑梗死患者(23.69±7.31)、(85.29±17.43)(P<0.05)。结论:在对急性脑梗死患者进行诊断的过程中,采取血清胱抑素C、凝血功能检验的临床效果较为显著,可较好的反映其病情变化程度,应用价值较高,值得进一步推广。
Objective:To analyze and explore the application effect of serocystatin C and coagulation function test in patients with acute cerebral infarction.Methods:64 cases of patients with acute cerebral infarction(study group)in a hospital from July 2018 to June 2020 and 64 health check-ups(control group)in the same period were selected and studied.Both groups of researchers were tested for serocystatin C and coagulation function,and the results were compared.Results:Taking serocystatin C and plasma fibrin as contrast indexes,the subjects in the control group were(1.08±0.24)mg/L and(2.63±1.02)g/L,while those in the observation group were(1.53±0.26)mg/L and(3.05±1.11)g/L,which were significantly higher in the observation group(P<0.05).The plasma prothrombin time and antithrombin-Ⅲindicators in the observation group were(15.38±3.49)and(66.54±18.59),which were significantly lower than(22.09±6.25)and(83.27±18.11)in the control group,and the difference was statistically significant(P<0.05).The serocystatin C and plasma fibrin in patients with advanced acute cerebral infarction were(1.52±0.09)mg/L and(3.09±1.15)g/L,which were significantly higher than(1.47±0.08)mg/L and(2.53±1.02)g/L in patients with complete acute cerebral infarction(P<0.05);The plasma prothrombin time and antithrombin-Ⅲindicators in patients with advanced acute cerebral infarction were(15.48±3.82)and(67.30±19.28),which were significantly lower than(23.69±7.31)and(85.29±17.43)in patients with complete acute cerebral infarction(P<0.05).Conclusion:In the process of diagnosis of patients with acute cerebral infarction,the clinical effect of serocystatin C and coagulation function test are relatively significant,which can better reflect the degree of disease change,has high application value,and is worthy of further promotion.
作者
张利明
刘大鹏
郭磊
甄明慧
聂曼杰
杨俊梅
Zhang Liming;Liu Dapeng;Guo Lei;Zhen Minghui;Nie Manjie;Yang Junmei(Zhengzhou Children's Hospital,Children's Hospital Affiliated to Zhengzhou University,Henan Provincial Children's Hospital,Zhengzhou Key Laboratory of Infection and Immunization of Children,Zhengzhou 450018)
出处
《数理医药学杂志》
CAS
2021年第10期1429-1431,共3页
Journal of Mathematical Medicine
基金
河南省卫生健康委科技计划(LHGJ20190971)。
关键词
血清胱抑素C
凝血功能检验
急性脑梗死
健康体检者
应用效果
serocystatin C
blood coagulation function test
acute cerebral infarction
health check-up
application effect