垂体后叶素与宫腔镜下负压清宫术治疗Ⅱ型剖宫产子宫瘢痕妊娠患者的临床效果探讨

The Clinical Effect of Hypophysin and Endoscopic Negative Pressure Removal in the Treatment of TypeⅡCesarean Section Uterine Scar Pregnancy

目的:探讨垂体后叶素与宫腔镜下负压清宫术治疗Ⅱ型剖宫产子宫瘢痕妊娠患者的临床效果。方法:选择2018年6月~2020年6月某院收治的Ⅱ型剖宫产子宫瘢痕妊娠患者86例,采用随机数字表法分为对照组和观察组各43例,两组均实施宫腔镜下负压清宫术,对照组联合子宫动脉栓塞术(UAE),观察组联合垂体后叶素,比较两组围术期指标、康复指标及并发症。结果:观察组手术时间(26.54±4.05)min、术后阴道出血时间(6.04±1.95)d、住院时间(4.96±0.75)d、月经恢复正常时间(31.57±5.31)d、β-HCG水平恢复正常时间(30.12±3.87)d,均短于对照组的(37.69±5.83)min、(11.34±2.46)d、(7.82±1.34)d、(37.89±6.45)d、(33.45±4.52)d;观察组术中出血量为(43.71±8.28)ml,少于对照组的(87.46±15.14)ml,观察组并发症发生率(4.65%)低于对照组(23.26%),差异有统计学意义(P<0.05)。结论:Ⅱ型剖宫产子宫瘢痕妊娠患者采用垂体后叶素与宫腔镜下负压清宫术治疗效果较好,利于改善围术期指标,加快患者术后恢复,减少并发症。

Objective: To investigate the clinical effect of hypophysin and endoscopic negative pressure removal in the treatment of patients with type Ⅱ cesarean section uterine scar pregnancy. Methods: From June 2018 to June 2020, 86 cases of type Ⅱ cesarean section uterine scar pregnancy patients treated in a hospital were selected and divided into two groups by random number table method, with 43 cases in each group. Both groups underwent endoscopic negative pressure removal, the control group was combined with uterine artery embolization(UAE), and the observation group was combined with pituitrin. The perioperative indicators, rehabilitation indicators and complications were compared between the two groups. Results: The operation time(26.54±4.05) min, postoperative vaginal bleeding time(6.04±1.95) d, hospitalization time(4.96±0.75) d, menstruation recovery time(31.57±5.31) d, and the time of β-HCG level returned to normal(30.12±3.87) d in the observation group were shorter than those in the control group [(37.69±5.83) min,(11.34±2.46) d,(7.82±1.34) d,(37.89±6.45) d,(33.45±4.52) d].The intraoperative blood loss in the observation group was(43.71±8.28) ml, which was less than that of the control group(87.46±15.14) ml.The incidence of complications in the observation group(4.65%) was lower than that of the control group(23.26%),and the difference was statistically significant(P<0.05). Conclusion: The treatment effect of pituitrin and endoscopic negative pressure removal in the treatment of type Ⅱ cesarean section uterine scar pregnancy patients is good, which is beneficial to improve the perioperative indicators, speed up the patients’ postoperative recovery, and reduce complications.