振动性骨骼肌损伤的研究进展

Research progress of vibration-induced skeletal muscle injury

职业性手臂振动病(HAVD)指作业工人长期从事手传振动作业而引起的职业性疾患,主要包括手臂部的循环、神经及骨骼肌功能的损伤。目前,振动对骨骼肌功能的影响越来越受到重视,研究振动性骨骼肌损伤(VSMI)发病机制是防治职业性HAVD的重要内容。本文结合国内外相关文献,对VSMI的病理改变、电生理研究、发生机制、临床诊断与防治以及研究方向等进行简要分析。

Occupational hand-arm vibration disease(HAVD)refers to the occupational disease caused by long-term hand-transmitted vibration operation, mainly including the injuries in functions of circulation, nerve system, skeletal muscle, etc. At present, more and more attention has been paid to the effect of vibration-induced skeletal muscle injury(VSMI),and the explore of pathogenesis of skeletal muscle impairment has become a research hotspot in the prevention and treatment of occupational HAVD.In this paper, the research progresses of VSMI were briefly reviewed and analyzed especially in pathologic changes, electrophysiological study, molecular mechanism, clinical diagnosis, treatment, prevention and research fields in future.