精神分裂症不同时期认知功能损害特点及干预方式的研究进展

Recent Advances in Cognitive Impairment in Schizophrenia:Stage-specific Features and Interventions

认知功能障碍贯穿于精神分裂症发生、发展的全过程,但其在疾病进程中的发展轨迹仍不清楚。本文从精神分裂症不同时期认知功能损害特点的角度出发,讨论了关于精神分裂症认知功能障碍的发生和发展过程,明确其发展轨迹以阐明精神分裂症的性质,并回顾了精神分裂症患者认知功能障碍的干预方式,发现精神分裂症患者的认知功能障碍随时间推移相对稳定,其本质可能为一种认知疾病,今后在临床诊断和治疗中需要从认知功能损害的预防、识别和干预等方面建立新的精神分裂症防控策略。

Although cognitive impairment occurs in each stage of schizophrenia,its specific trajectory in the development of schizophrenia is still unclear.We analyzed the overall development and stage-specific features of cognitive impairment in schizophrenia,then clarified its developmental trajectory,summarized that temporal changes of cognitive impairment are relatively insignificant,and reviewed relevant interventions.After that,we inferred that schizophrenia may be a cognitive disease in essence,and recommended that future diagnosis and treatment strategies for schizophrenia should be developed based on prevention,recognition and intervention of cognitive impairment.