经皮椎体成形术中采用新型Vessel-X骨材料填充器治疗骨质疏松性椎体压缩性骨折

Treatment of osteoporotic vertebral compression fracture with new Vessel-X bone filler in percutaneous vertebroplasty

目的对比经皮椎体成形术(PVP)中采用新型Vessel-X骨材料填充器(Vessel-PVP)与传统PVP治疗老年骨质疏松性椎体压缩性骨折(OVCF)的临床疗效及安全性。方法2015年6月—2018年12月,本院收治老年OVCF患者119例,前期67例采用传统PVP治疗(对照组),后期52例采用Vessel-PVP治疗(观察组)。记录并比较2组手术时间、住院时间、手术前后椎体前缘高度、椎体高度恢复率及骨水泥渗漏发生率,采用疼痛视觉模拟量表(VAS)评分评估疼痛缓解情况。结果所有手术顺利完成。患者随访12~19(15.31±2.71)个月。2组术后7 d、术后12个月的VAS评分及伤椎前缘高度较术前明显改善,差异均有统计学意义(P<0.05);组间差异无统计学意义(P>0.05)。2组骨水泥注入量、手术时间、住院时间、椎体高度恢复率及骨水泥渗漏率差异均无统计学意义(P>0.05)。结论Vessel-PVP治疗老年OVCF临床疗效及安全性满意,但较PVP并未显现出明显优势,且操作更为耗时,仍应将PVP作为首选术式。

Objective To compare the clinical efficacy and safety of percutaneous vertebroplasty(PVP)with new Vessel-X bone filler(Vessel-PVP)and traditional PVP in the treatment of senile osteoporotic vertebral compression fractures(OVCF).Methods From June 2015 to December 2018,119 elderly patients with OVCF were treated in our hospital.In the early stage,67 patients were treated with traditional PVP(control group),and in the late stage,52 patients were treated with Vessel-PVP(observation group).The operation time,hospital stay,anterior edge height of injured vertebra before and after operation,vertebral height recovery rate and the incidence of bone cement leakage were recorded and compared between the 2 groups.Visual analogue scale(VAS)score was used to evaluate the degree of pain relief.Results All the operations were successfully completed.All the patients were followed up for 12-19(15.31±2.71)months.The VAS score and the anterior edge height of injured vertebra were significantly improved in both groups at 7 d and 12 months after operation,and the differences were statistically significant(P<0.05);there was no significant difference between the 2 groups(P>0.05).There was no significant difference in the amount of bone cement injection,operation time,hospital stay,vertebral height recovery rate and cement leakage rate between the 2 groups(P>0.05).Conclusions The clinical efficacy and safety of Vessel-PVP in the treatment of senile OVCF are satisfactory,but it does not show obvious advantages compared with PVP,and the operation is more time-consuming,so PVP should still be the first choice.