超早期介入栓塞治疗颅内破裂动脉瘤患者的效果

Effects of ultra-early interventional embolization in treatment of patients with ruptured intracranial aneurysms

目的:观察超早期介入栓塞治疗颅内破裂动脉瘤患者的效果。方法:选取94例颅内破裂动脉瘤患者为研究对象,按照随机数字表法分为对照组和观察组各47例。对照组行非超早期(发病24 h后)介入栓塞治疗,观察组行超早期(发病24 h内)介入栓塞治疗,比较两组卧床时间、住院时间、治疗费用、美国国立卫生院卒中量表(NIHSS)评分、蒙特利尔认知评估量表(MoCA)评分和并发症发生率。结果:观察组卧床时间、住院时间均短于对照组,治疗费用明显低于对照组,差异有统计学意义(P<0.05);治疗后,两组MoCA评分均高于治疗前,且观察组高于对照组,两组NIHSS评分均低于治疗前,且观察组低于对照组,差异有统计学意义(P<0.05);观察组并发症发生率为12.78%,低于对照组的29.79%,差异有统计学意义(P<0.05)。结论:超早期介入栓塞治疗颅内破裂动脉瘤患者可缩短卧床时间和住院时间,提高MoCA评分,以及降低治疗费用、NIHSS评分和并发症发生率,优于非超早期介入栓塞治疗效果。

Objective:To investigate effects of ultra-early interventional embolization in treatment of patients with ruptured intracranial aneurysms.Methods:94 patients with ruptured intracranial aneurysms were selected as the research objects,and were divided into control group and observation group according to the random number table method,47 cases in each group.The control group received non-ultra-early(24 hours after onset)interventional embolization,while the observation group was given the ultra-early(within 24 hours)interventional embolization.The bed rest time,the hospitalization time,the treatment cost,the National Institutes of Health Stroke Scale(NIHSS)score,the Montreal cognitive assessment scale(MoCA)score and the complication rate were compared between the two groups.Results:The bed rest time and the hospitalization time in the observation group were shorter than those in the control group;the treatment cost was significantly lower than that in the control group;and the differences were statistically significant(P<0.05).After treatment,the MoCA scores of the two groups were higher than those before the treatment,and that of the observation group was higher than that of the control group;the NIHSS scores of the two groups were lower than those before the treatment,and that of the observation group was lower than that of the control group;and the differences were statistically significant(P<0.05).Further,the incidence of complications in the observation group was 12.78%,which was lower than 29.79%in the control group,and the difference was statistically significant(P<0.05).Conclusions:Ultra-early interventional embolization in the treatment of the patients with ruptured intracranial aneurysms can shorten the bed rest time and the hospitalization time,improve the MoCA score,and reduce the treatment cost,the NIHSS score and the complication rate.Moreover,it is superior to non-ultra-early interventional embolization.