左炔诺孕酮硅胶棒皮下埋植联合高强度聚焦超声治疗子宫腺肌病患者的效果

Effects of Levonorgestral silastic implant subcutaneous implantation combined with high intensity focused ultrasound in treatment of patients with adenomyosis

目的:观察左炔诺孕酮硅胶棒皮下埋植联合高强度聚焦超声治疗子宫腺肌病患者的效果。方法:选取84例子宫腺肌病患者进行前瞻性研究,按照随机数字表法分为对照组和观察组各42例。对照组给予高强度聚焦超声治疗,观察组在对照组基础上联合左炔诺孕酮硅胶棒皮下埋植治疗,比较两组手术相关指标水平和不良反应发生率。结果:治疗后,观察组月经量少于对照组,子宫体积小于对照组,视觉模拟评分法评分低于对照组,差异均有统计学意义(P<0.05);两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:左炔诺孕酮硅胶棒皮下埋植联合高强度聚焦超声治疗子宫腺肌病患者可减少月经量,缩小子宫体积,减轻疼痛,其效果优于单纯高强度聚焦超声治疗。

Objective:To evaluate effects of Levonorgestral silastic implant subcutaneous implantation combined with high intensity focused ultrasound in treatment of patients with adenomyosis.Methods:84 patients with adenomyosis were selected as the research objects,and were divided into control group and observation group according to the random number table method,42 cases in each group.The control group was given high intensity focused ultrasound therapy,while the observation group was combined with Levonorgestral silastic implant subcutaneous implantation on the basis of that of the control group.The levels of surgery-related indicators and the incidence of adverse reactions were compared between the two groups.Results:After the treatment,the menstrual volume of the observation group was less than that of the control group;the uterine volume was smaller than that of the control group;the VAS score was lower than that of the control group;and the differences were statistically significant(P<0.05).However,there was no statistically significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusions:The Levonorgestral silastic implant subcutaneous implantation combined with high intensity focused ultrasound in treatment of the patients with adenomyosis can reduce the menstrual volume,reduce the uterine volume,and reduce the pain score.Moreover,it is superior to single high intensity focused ultrasound therapy.