我国血液净化病人抗凝治疗研究现状的可视化分析

Research status quo of anticoagulant treatment of patients with hemopurification in China:a visualized analysis

目的:基于可视化分析方法对我国血液净化病人抗凝治疗相关文献进行分析,整体把握我国血液净化病人抗凝治疗现状,为我国抗凝治疗提供相关依据。方法:检索中国生物医学文献数据库、万方数据资源和中国知网数据库自建库至2021年1月1日文献,纳入所有中文发表的血液净化病人抗凝治疗相关研究。采用BICOMS 2分析软件对文献主要信息进行提取、分析并生成共现矩阵;并使用Ucinet 6.0和gCluto 1.0软件绘制可视化图谱。结果:共提取文献3688篇,自1982年发表第一篇后逐年增长,至2013年文献量到达高峰。全国31个省市、自治区和直辖市均有研究发表,总体上发达地区发表的文献数量多于欠发达地区,作者之间和研究机构之间的合作较少,尤其是不同地域之间的合作。纳入研究作者达5798人,但仅23名作者(3.96%)参与20篇及以上的论文发表。基金支持文献比例仅15.83%,载文量>30篇的期刊28种,累积刊登文献量1111篇(30.12%)。血液净化病人抗凝治疗研究主要集中于抗凝药物的选择、用量、抗凝方式及并发症等方面。结论:我国血液净化病人抗凝治疗相关研究仍不成熟,并且领域内作者、研究机构之间的合作偏低,科研基金资助论文比例不高,后续研究应注重获取科研基金资助并加强合作。

Objective:To analyze the relevant literature and understand the overall status quo of anticoagulation treatment of patients with hemopurification in China based on the visualized analysis method and provide a relevant basis for anticoagulation treatment in China.Methods:Literature published in Chinese related to the anticoagulation treatment of patients with hemopurification was retrieved from the Chinese Biomedical Literature Database,Wanfang Database,and the China National Knowledge Infrastructure(CNKI)from establishment until January 1,2021.BICOMS 2 analysis software was used to extract and analyze the main information of the literature and generate a co-occurrence matrix.Ucinet 6.0 and gCluto 1.0 softwares were used to draw a visual map.Results:A total of 3,688 documents were extracted,which increased year by year since the first one was published in 1982 and peaked in 2013.Literature was published in all 31 provinces,municipalities,autonomous regions,and municipalities across the country.Generally,the number of documents published in developed regions was more than that in less developed regions.There was less cooperation between authors and research institutions,especially between different regions.A total of 5798 authors were included,but only 23(3.96%)participated in 20 or more papers.Literature supported by fund accounted for only 15.83%of all literature.A total of 28 journals published more than 30 articles,and 1111 articles(30.12%)as accumulated.The research on the anticoagulation treatment of patients with hemopurification mainly focused on the selection,dosage,anticoagulation methods,and complications of anticoagulation drugs.Conclusions:The study on the anticoagulation treatment of patients with hemopurification in China is still immature.The cooperation between authors and research institutions in the field is low,and the proportion of scientific-funded research is not high.Follow-up research should focus on obtaining scientific research funding and strengthening cooperation.