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对酒精性心肌病采用β-受体阻滞剂治疗的临床疗效及心功能改善评估

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摘要 目的:探讨对酒精性心肌病采用β-受体阻滞剂治疗的临床疗效以及对患者心功能改善的效果。方法:选取收治的80例酒精性心肌病患者为研究对象,随机分为观察组和对照组各40例,对照组患者应用曲美他嗪治疗,观察组患者通过卡维地洛进行治疗,比较两组患者的临床疗效、治疗前后收缩压与舒张压改善情况以及左心射血分数(LVEF)和C-反应蛋白(CRP)心功能指标改善情况。结果:两组患者的临床治疗总有效率均为95%,其中观察组显效20例,有效18例,无效2例,对照组患者显效21例,有效17例,无效2例,差异无统计学意义(P>0.05)。治疗后两组患者舒张压与收缩压均明显下降,下降幅度及血压控制情况相当,差异无统计学意义(P>0.05)。而在心功能指标改善方面,两组患者在治疗前LVEF及CRP接近的情况下,差异无统计学意义(P>0.05),治疗后LVEF有所上升,CRP有所下降,观察组患者改善幅度好于对照组,差异有统计学意义(P<0.05)。结论:酒精性心肌病患者采用卡维地洛β-受体阻滞剂进行治疗,疗效显著,能够帮助患者降低血压指标,改善心功能,具有很高的应用价值。
作者 陈彬 陈智娇
出处 《吉林医学》 CAS 2021年第10期2434-2435,共2页 Jilin Medical Journal
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