摘要
肝纤维化是多种慢性肝病发展为肝硬化甚至肝癌的关键病理过程。中医药在抗肝纤维化过程中发挥了重要的作用。文章基于对络病理论的认识,认为肝纤维化病机是经络气虚为本,脉络瘀滞为标。治疗当以通为用,予辛味虫蚁通络与补虚通络相结合,标本并治,可使气血通畅,肝积得消。此外,络病理论与其他肝纤维化病机理论如“虚损生积”论、“主客交”论亦有着密切的联系,综合各论,总以通络补虚结合,疗效可观,以资为鉴。
Hepatic fibrosis is the key pathological process in the development of cirrhosis and hepatocellular carcinoma.Traditional Chinese medicine has played an important role in the antifibrotic therapy.Based on the understanding of collateral disease theory,this paper holds that the pathogenesis of hepatic fibrosis is deficiency of meridians on root cause and stagnation of collaterals on manifestation.The treatment should be based on dredging,combining acrid drug and insect drug and tonifying deficiency to dredge collaterals.Treatment both manifestation and root cause can make qi and blood unobstructed and liver accumulation disappear.In addition,the theory of collateral disease is closely related to other pathogenesis theories of hepatic fibrosis,such as the theory of‘asthenia and deficiency cause accumulation’,and the theory of‘zhukejiao’.Based on the above theories,the combination of dredging collaterals and tonifying deficiency is effective,which can be used for reference.
作者
李霞
吴文军
刘文平
郑燕凤
冯全生
LI Xia;WU Wen-jun;LIU Wen-ping;ZHENG Yan-feng;FENG Quan-sheng(School of Basic Medicine,Chengdu University of TCM,Chengdu 611137,China)
出处
《中华中医药杂志》
CAS
CSCD
北大核心
2021年第8期4619-4622,共4页
China Journal of Traditional Chinese Medicine and Pharmacy
基金
国家自然科学基金面上项目(No.82074399)
四川省科技厅重点研发项目(No.2020YFS0301)
四川省科技厅应用基础研究项目(No.2021YJ0253)。
关键词
肝纤维化
络病理论
以通为用
经络气虚
脉络瘀滞
虚损生积
主客交
Hepatic fibrosis
Collateral disease theory
Utilization of dredging method
Deficiency of meridians
Stagnation of collaterals
Asthenia and deficiency cause accumulation
Zhukejiao