徐志瑛从《难经》“肺熟”理论辨治特发性肺纤维化思路探析

Thoughts of XU Zhi-ying in treating idiopathic pulmonary fibrosis based on the theory of‘Fei shu’from Nanjing

“肺熟”理论源自《难经·三十三难》。通过文献梳理发现,“肺熟”是一类以“孔窍窒实”为表现的慢性虚损性疾病,病机衍化特点为“肺蒙虚火-痰瘀互结-阳虚气衰”。《难经》“肺熟”理论与特发性肺纤维化(IPF)有其理论相关性,主要表现在病因病机、临床征象和形态表现3个方面。徐志瑛教授临证治疗IPF善用清热养阴、祛痰逐瘀、益气温肾之法,可为临床诊疗提供新的思路。

‘Fei shu’theory is originated from Chinese medical classic named Nanjing·Thirty-three Nan.Through the way of document combing,we found that‘Fei shu’is a kind of chronic deficiency disease with the performance of‘pore asphyxia solid’.The pathogenesis of‘Fei shu’is‘lung invaded by deficient fire-phlegm and blood stasis interaction-yang deficiency and qi weakness’.‘Fei shu’theory from Nanjing is tightly associated with idiopathic pulmonary fibrosis(IPF),mainly in pathogenic characteristic,symptoms and sighs,pathological manifestation.Professor XU Zhi-ying argued that the clinical treatment can flexibly use the methods of clearing heat and demonstrating lungs,removing phlegm and stasis,and benefiting yang and tonifying qi,which can provide new ideas for clinical treatment.