骶神经调控疗法治疗慢性传输型便秘患者的临床疗效分析

Sacral neuro modulation for chronic transit constipation:a clinical analysis of 10 cases

目的:评估骶神经调控疗法治疗慢性传输型便秘的临床效果。方法:回顾性分析2017年7月至2018年5月滨州医学院附属医院治疗的10例经骶神经调控疗法治疗的便秘患者,根据排粪日记、Wexner便秘评分、便秘患者生存质量量表及胃肠道生活质量指数进行疗效评价。结果:本组10例患者中9例患者植入永久性骶神经刺激器,患者术后症状较术前明显改善,差异具有统计学意义(P<0.01);术后患者的躯体不适、心理不适、担心及焦虑症状较术前明显改善,差异均有统计学意义(均P<0.01);术后患者的Wexner便秘评分较术前差异有统计学意义(P<0.01)。结论:骶神经调控疗法是一种安全有效、操作简单、微创可逆的治疗慢性传输型便秘的新方法。

Objective To assess the clinical effects of sacral nerve regulation therapy for patients with chronic transit constipation.Methods A total of 10 patients were treated with sacral nerve regulation therapy at our department from Jul 2017 to May 2018.The efficacy was assessed by bowel habit diary,Wexner constipation scores,constipation patients'quality of life scale and gastrointestinal quality of life index.Results Nine patients were implanted with permanent sacral nerve stimulator with the analysis of constipation patients'quality of life scale,the postoperative symptoms were significantly improved compared with those before operation(P<0.01),and the symptoms of physical discomfort,psychological discomfort,worry and anxiety were also significantly improved after operation,with statistical significance(all P<0.01).The Wexner constipation score was significantly higher after operation(P<0.01).Conclusion SNM is a clinically safe,efficacious,simple,minimally invasive and reversible new technique for the treatment of chronic transit constipation.