优化扫描矩阵对脑肿瘤患者头部多体素氢质子磁共振波谱成像的临床应用价值

Clinical Application Value of Optimized Scanning Matrix for Head Multivoxel Hydrogen Proton Magnetic Resonance Spectroscopy in Patients with Brain Tumor

目的探讨改变磁共振扫描矩阵大小对脑肿瘤患者头部多体素氢质子磁共振波谱成像的临床应用价值。方法20位脑肿瘤患者,使用Siemens skyra 3.0 T磁共振扫描仪20通道的头颈联合线圈分别用16×16,8×8扫描矩阵进行氢质子磁共振波谱扫描。由两位高年资诊断医师单独评价修改扫描矩阵前后图像的信噪比(Signal to Noise Ratio,SNR)、半峰宽、主要代谢物浓度等波谱质量判别指标,并对结果进行统计学分析。结果研究对象在解析矩阵不变,扫描矩阵减小一倍的情况下,主要代谢物浓度不变,修改前扫描矩阵16×16,SNR为4.7±2.812,修改后扫描矩阵8×8,SNR为9.15±6.277,信噪比更好,差异有统计学意义(P<0.05)。结论多体素氢质子磁共振波谱扫描中,扫描矩阵的减小在保证波谱图像质量的同时缩短了扫描时间,具有一定临床应用价值。

Objective To explore the clinical value of changing the size of scanning matrix for head multivoxel hydrogen proton magnetic resonance spectroscopy(MRS)imaging in patients with brain tumor.Methods Twenty patients with brain tumors were scanned with Siemens Skyra 3.0 T MR scanner.The head and neck joint coils of 20 channels were used with 16×16,8×8 scanning matrix for hydrogen proton MRS respectively.Two senior diagnostic physicians separately evaluated the spectral quality discrimination indexes such as signal-to-noise ratio(SNR),full width at half maximum and concentration of major metabolites before and after the modification of scanning matrix;the results were statistically analyzed.Results Under the condition that the analytical matrix is unchanged and the scanning matrix was reduced by half,the concentration of main metabolites remains unchanged,the SNR of the 16×16 scanning matrix was 4.7±2.812,while the SNR of the 8×8 scanning matrix was 9.15±6.277.The SNR become better,and the difference was statistically significant(P<0.05).Conclusion The reduction of scanning matrix during multivoxel hydrogen proton MRS scanning can ensure the quality of spectral images and shorten the scanning time,which has certain clinical application value.