高分辨电感耦合等离子体质谱测量氯化锶[^(89)Sr]原料中铝含量

The Determination of Aluminum Content in^(89)SrCl_(2) Crude Material by HR-ICP-MS

为准确测量氯化锶[^(89)Sr]溶液中铝含量以控制产品质量和指导生产工艺改进,采用高分辨电感耦合等离子体质谱(HR-ICP-MS)测量氯化锶[^(89)Sr]原料中的铝含量,建立样品准备和标准工作曲线绘制的方法,优化质谱条件。通过对比实验考察盐酸体系、酸度和锶基体对铝测量的影响,研究质谱干扰、铝本底的来源及消除方式,开展内标选择实验。结果表明,盐酸体系对铝含量测量无显著影响,0.5%HCl体系可作为标准和样品稀释定容的基体溶液;分辨率为4000(峰谷高度为峰高的10%)时可消除铝的双电荷干扰及多原子离子干扰,优选钇作为内标元素;该方法的检出限为39 ng/L。本研究建立的方法可快速准确测量氯化锶[^(89)Sr]溶液中的铝含量,结果满足产品质量控制和工艺改进的要求。

The content of aluminum in ^(89)SrCl_(2)crude material is an important parameter for quality control.The accurate measurement of that in ^(89)SrCl_(2)solution is the basis of quality control and process improvement.In this paper,we use HR-ICP-MS to determine the aluminum content in ^(89)SrCl_(2)solution,and we have established the method of sample preparation and constructing calibration curve,and the optimal mass spectrometry conditions were also determined.The effect of hydrochloric acid system,acidity and strontium matrix on the measurement of aluminum concentration were studied by a series of contrast experiments.Moreover,the source and the elimination method of mass spectrum interferences and aluminum background were also investigated by internal standard selection experiments.The experimental results show that the hydrochloric acid system has no significant effect on the measurement,and the 0.5%HCl system can be used as the matrix solution for standard and sample dilution.When the yttrium was selected as the internal standard,the double charged ion interferences and polyatomic ion interferences of aluminum could be eliminated with a resolution of 4000(10%valley),and the detection limit of this method could reach 39 ng/L.The method here can be used to measure the content of aluminum in ^(89)SrCl_(2)solution quickly and accurately,which can meet the requirements of product quality control and process improvement.