苏州市吴江地区妊娠期血脂参考值范围的探讨

Discussion on the reference range of blood lipids during pregnancy in Wujiang area of Suzhou city

目的观察苏州市吴江地区妊娠不同时期血脂水平分布情况,建立本地区的参考范围。方法将在我院建册系统检查至足月分娩的单胎妊娠1388例孕妇作为研究对象,通过对孕11~13^(+6)周,孕28~31^(+6)周,孕35~36^(+6)周,孕38~41^(+6)周四个不同孕期的血液中甘油三酯、总胆固醇、低密度脂蛋白和高密度脂蛋白的检查结果进行统计分析,初步建立本地区妊娠各时期孕妇血脂的参考范围。结果妊娠期血脂水平会随孕期逐渐升高,孕中后期明显超过非孕期水平。结论妊娠期的血脂不适合用非孕期的参考标准进行分析与管理,本研究以百分位数法划定本地区正常值参考范围,供临床医师对妊娠不同时期血脂结果进行合理解读。

Objective:To observe the distribution of blood lipids during different gestation periods in Wujiang District of Suzhou City,to establish the reference range of this region,and to provide reference for clinicians to make decisions.Methods:A total of 1388 pregnant women with single pregnancy who were registered in our hospital until their delivery to full term were selected as the research subjects.The blood triglyceride,total cholesterol,low density lipoprotein and high density lipoprotein of 11 to 13^(+6) weeks of pregnancy,28 to 31^(+6) weeks of pregnancy,35 to 36^(+6) weeks of pregnancy and 38 to 41^(+6) weeks of pregnancy were analyzed statistically to establish the reference range of blood lipids of pregnant women at various stages of pregnancy in the local area.Results:The level of blood lipid during pregnancy gradually increased with pregnancy and obviously exceeded the level of non-pregnancy after the middle and late pregnancy.Conclusion:Pregnant women have physiological blood lipid elevation,and the reference range of normal values in this area is defined by percentile method,so as to provide clinicians with reasonable interpretation of blood lipid results at different stages of pregnancy.